9ZP4

E. coli RNA polymerase elongation complex containing the unnatural dZ:PTP base pair in a trigger-loop-closed conformation

Summary for 9ZP4

Entry DOI	10.2210/pdb9zp4/pdb
EMDB information	74516
Descriptor	DNA-directed RNA polymerase subunit alpha, (5S)-2-amino-8-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}imidazo[1,2-a][1,3,5]triazin-4(8H)-one, DNA-directed RNA polymerase subunit beta, ... (11 entities in total)
Functional Keywords	e. coli rna polymerase elongation complex containing the unnatural dz:ptp base pair in a trigger-loop-closed conformation, transcription, transcription-dna-rna complex, transcription/dna/rna
Biological source	Escherichia coli More
Total number of polymer chains	8
Total formula weight	382150.16
Authors	Li, Q.,Benner, S.A.,Wang, D. (deposition date: 2025-12-16, release date: 2026-09-02)
Primary citation	Li, Q.,Benner, S.A.,Wang, D. Structural Basis of Transcription of the Hachimoji Eight-Letter Alphabet by E. coli RNA Polymerase To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.42 Å)

Structure validation