9Z0Y

Crystal structure of Neisseria gonorrhoeae penicillin-binding protein 2 from strain FA19 containing seven resistance mutations and three epistatic mutations

Summary for 9Z0Y

• Entry DOI: 10.2210/pdb9z0y/pdb
• Descriptor: Penicillin-binding protein 2 (2 entities in total)
• Functional Keywords: penicillin-binding protein, transpeptidase domain, n. gonorrhoeae, antibiotic resistance, hydrolase
• Biological source: Neisseria gonorrhoeae FA19
• Total number of polymer chains: 2
• Total formula weight: 70714.73

Authors

Singh, A.,Bala, S.,Davies, C. (deposition date: 2025-11-03, release date: 2026-03-04)

• Primary citation: Bivins, M.M.,Tomberg, J.,Bagshaw, M.,Singh, A.,Bala, S.,Davies, C.,Nicholas, R.A.; Interrogating the Delicate Balance between Antibiotic Resistance and Enzymatic Function in Penicillin-Binding Protein 2 Mutations from Ceftriaxone-Resistant Neisseria gonorrhoeae strain H041; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.46 Å)