9Z0Y
Crystal structure of Neisseria gonorrhoeae penicillin-binding protein 2 from strain FA19 containing seven resistance mutations and three epistatic mutations
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Penicillin-binding protein 2 | polymer | 329 | 35357.4 | 2 | UniProt (A0AB74EE38) | Neisseria gonorrhoeae FA19 | PBP-2, Probable peptidoglycan D,D-transpeptidase PenA |
| 2 | C, D (A, B) | water | water | 18.0 | 401 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 574 (UniProt: A0AB74EE38)
| PDB | External Database | Details |
|---|---|---|
| Gly 232 | - | expression tag |
| Ser 233 | - | expression tag |
| Gly 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Gly 297 | Ala 283 | conflict |
| - | Tyr 284 | deletion |
| - | Asp 285 | deletion |
| - | Pro 286 | deletion |
| - | Asn 287 | deletion |
| - | Arg 288 | deletion |
| - | Pro 289 | deletion |
| - | Gly 290 | deletion |
| - | Arg 291 | deletion |
| - | Ala 292 | deletion |
| - | Asp 293 | deletion |
| - | Ser 294 | deletion |
| - | Glu 295 | deletion |
| - | Gln 296 | deletion |
| - | Arg 297 | deletion |
| Val 311 | Ala 311 | engineered mutation |
| Met 312 | Ile 312 | engineered mutation |
| Pro 316 | Val 316 | engineered mutation |
| Val 437 | Ala 437 | engineered mutation |
| Val 447 | Leu 447 | engineered mutation |
| Ile 462 | Phe 462 | engineered mutation |
| Ser 483 | Thr 483 | engineered mutation |
| Leu 504 | Phe 504 | engineered mutation |
| Tyr 512 | Asn 512 | engineered mutation |
| Ser 545 | Gly 545 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70714.7 | |
| All* | Total formula weight | 70714.7 |
