9YUB

The crystal structure of human abl1 T315I mutant kinase domain in complex with PH-ELV-1022

This is a non-PDB format compatible entry.

Summary for 9YUB

• Entry DOI: 10.2210/pdb9yub/pdb
• Related: 9YU9
• Descriptor: Tyrosine-protein kinase ABL1, (1S,2S)-N-[2-(4,6-dimethoxypyrimidin-5-yl)-1-methyl-1H-pyrrolo[2,3-c]pyridin-5-yl]-2-fluorocyclopropane-1-carboxamide (3 entities in total)
• Functional Keywords: inhibitor, complex, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33918.60

Authors

Chao, A.,DuPrez, K.T.,Lyssikatos, J.P.,Kintz, S.,Han, F. (deposition date: 2025-10-22, release date: 2026-10-28)

• Primary citation: Chao, A.,DuPrez, K.T.,Han, F.; The crystal structure of human abl1 T315I mutant kinase domain in complex with PH-ELV-1022; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)