9YR9

Structure of human MARK3 in complex with inhibitor

This is a non-PDB format compatible entry.

Summary for 9YR9

• Entry DOI: 10.2210/pdb9yr9/pdb
• Descriptor: MAP/microtubule affinity-regulating kinase 3, 3-({5-chloro-2-[2-(difluoromethoxy)-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl}amino)thiophene-2-carboxamide (3 entities in total)
• Functional Keywords: hippo pathway, protein kinase, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 75886.65

Authors

Mao, D.Y.L.,Ogunjimi, A.A.,Pau, V.,Chini, F.D.,Sicheri, F. (deposition date: 2025-10-16, release date: 2026-04-08)

• Primary citation: Mao, D.Y.L.,Ogunjimi, A.A.,Pau, V.,Chini, F.D.,Sicheri, F.; Structure of human MARK3 in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.402 Å)