9YDG

Crystal structure of the human DCAF1 WDR domain in complex with OICR-41074

This is a non-PDB format compatible entry.

Summary for 9YDG

• Entry DOI: 10.2210/pdb9ydg/pdb
• Descriptor: DDB1- and CUL4-associated factor 1, (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-[(1E)-3-(morpholin-4-yl)-3-oxoprop-1-en-1-yl]-1H-pyrrole-3-carboxamide, SODIUM ION, ... (5 entities in total)
• Functional Keywords: wd-repeat, wdr, dcaf1, sgc, structural genomics, psi-2, protein structure initiative, structural genomics consortium, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72448.75

Authors

kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Mamai, A.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2025-09-22, release date: 2025-11-12)

• Primary citation: kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Mamai, A.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Crystal structure of the human DCAF1 WDR domain in complex with OICR-41074; To be published,

Experimental method

X-RAY DIFFRACTION (1.54 Å)