9YD1

Crystal structure of BF DNA polymerase F710Y mutant bound to tetrahydrofuran and dATP

Replaces:  6UEU

Summary for 9YD1

• Entry DOI: 10.2210/pdb9yd1/pdb
• Related: 6E96
• Related PRD ID: PRD_900003
• Descriptor: DNA polymerase I, DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(2DT))-3'), DNA (5'-D(*CP*GP*(3DR)P*AP*CP*GP*TP*GP*AP*TP*CP*G)-3'), ... (8 entities in total)
• Functional Keywords: replication
• Biological source: Geobacillus stearothermophilus; More
• Total number of polymer chains: 6
• Total formula weight: 146679.08

Authors

Wu, E.Y.,Beese, L.S. (deposition date: 2025-09-20, release date: 2026-06-24)

• Primary citation: Walsh, A.R.,Beese, L.S.,Wu, E.Y.; Structural basis for blockage of DNA synthesis by a thymine dimer lesion in a high-fidelity DNA polymerase; Biochemistry, 2026; DOI: 10.1021/acs.biochem.5c00781

Experimental method

X-RAY DIFFRACTION (1.8 Å)