9Y9K

HIV-1 Nef SF2 Core Domain Bound To The Human Hck SH3 Domain

Summary for 9Y9K

• Entry DOI: 10.2210/pdb9y9k/pdb
• Related: 9Y58
• Descriptor: Protein Nef, Tyrosine-protein kinase HCK, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: hiv-1, nef, src family kinase, hck, protein complex, viral protein
• Biological source: HIV-1 M:B_ARV2/SF2; More
• Total number of polymer chains: 2
• Total formula weight: 26396.60

Authors

Alvarado, J.J.,Smithgall, T.E. (deposition date: 2025-09-14, release date: 2026-07-22)

• Primary citation: Thomas, C.E.,Alvarado, J.J.,Smithgall, T.E.; HIV-1 Nef Homodimerization as a Structural Mechanism for Kinase Activation and Small Molecule Inhibitor Action; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.34 Å)