9Y9K
HIV-1 Nef SF2 Core Domain Bound To The Human Hck SH3 Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein Nef | polymer | 149 | 17592.9 | 1 | UniProt (P03407) Pfam (PF00469) | HIV-1 M:B_ARV2/SF2 | 3'ORF,Negative factor,F-protein |
| 2 | B (B) | Tyrosine-protein kinase HCK | polymer | 73 | 8555.5 | 1 | UniProt (P08631) Pfam (PF00018) | Homo sapiens (human) | Hematopoietic cell kinase,Hemopoietic cell kinase,p59-HCK/p60-HCK,p59Hck,p61Hck |
| 3 | C, E, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | D (A) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) PubChem (943) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A: 62 - 209 (UniProt: P03407)
B: 80 - 144 (UniProt: P08631)
| PDB | External Database | Details |
|---|---|---|
| Met 61 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 79 | - | initiating methionine |
| Leu 145 | - | expression tag |
| Glu 146 | - | expression tag |
| His 147 | - | expression tag |
| His 148 | - | expression tag |
| His 149 | - | expression tag |
| His 150 | - | expression tag |
| His 151 | - | expression tag |
| His 152 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26148.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.2 | |
| All* | Total formula weight | 26396.6 |
