9Y4W

Eukaryotic translation initiation factor 2-B (eIF2B) with a truncation in the beta subunit (active-like-state) asymmetrically bound to the viral effector AcP10

Summary for 9Y4W

• Entry DOI: 10.2210/pdb9y4w/pdb
• EMDB information: 72462 72463 72466 72467 72468 72477 72499
• Descriptor: Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... (10 entities in total)
• Functional Keywords: guanine nucleotide exchange factor, gef, translation, initiation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 547445.83

Authors

Dalwadi, U.,Croll, T.,Subramanian, A.,Lee, D.J.,Arthur, C.,Walter, P.,Frost, A. (deposition date: 2025-09-04, release date: 2026-06-24)

• Primary citation: Dalwadi, U.,Croll, T.,Subramanian, A.,Lee, D.J.,Arthur, C.,Walter, P.,Frost, A.; Allosteric Disordering of eIF2B Regulates the Integrated Stress Response; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)