9XY4

Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (370) Complex Bound by the MEDI3622 Fab

Summary for 9XY4

• Entry DOI: 10.2210/pdb9xy4/pdb
• EMDB information: 72322
• Descriptor: Inactive rhomboid protein 1, MEDI3622 Fab Heavy Chain, MEDI3622 Fab Light Chain, ... (8 entities in total)
• Functional Keywords: complex, membrane protein, enzyme, adam, rhomboid, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 173173.11

Authors

Ungvary, J.N.,Maciag, J.J.,Seegar, T.C.M. (deposition date: 2025-08-25, release date: 2026-04-01)

• Primary citation: Ungvary, J.N.,Maciag, J.J.,Seegar, T.C.M.; Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (370) Complex Bound by the MEDI3622 Fab; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.12 Å)