9XJP

Structure of the CX3CL1.44-US28-GqiN18-scFv16 in the E-state, chemokine domain fully modeled

Summary for 9XJP

• Entry DOI: 10.2210/pdb9xjp/pdb
• Related: 9XH2
• EMDB information: 66942
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: membrane protein, gpcr, intermediate state, gdp, engineered chemokine, hcmv, viral protein, viral-host interaction
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 167081.31

Authors

Jude, K.M.,Garcia, K.C.,Tsutsumi, N. (deposition date: 2025-11-05, release date: 2026-09-23)

• Primary citation: Jude, K.M.,Garcia, K.C.,Tsutsumi, N.; Structural basis of a stepwise Gq activation by a chemokine receptor US28; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.74 Å)