9XBT

Crystal structure of human SIRT5 in complex with inhibitor 728

This is a non-PDB format compatible entry.

Summary for 9XBT

• Entry DOI: 10.2210/pdb9xbt/pdb
• Descriptor: NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION, 3-[3-[[2-[(2-chlorophenyl)amino]-5-[[(1~{S})-1-phenylpropyl]carbamoyl]pyrimidin-4-yl]amino]propylcarbamothioylamino]propanoic acid, ... (4 entities in total)
• Functional Keywords: hydrolase, hydrolase inhibitor, sirt5
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 59835.81

Authors

Yang, L.-L.,Jiang, Y.-Y. (deposition date: 2025-10-24, release date: 2026-10-28)

• Primary citation: Yang, L.-L.,Jiang, Y.-Y.; Crystal structure of human SIRT5 in complex with inhibitor 728; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.141 Å)