9XBT

Crystal structure of human SIRT5 in complex with inhibitor 728

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NAD-dependent protein deacylase sirtuin-5, mitochondrial	polymer	269	29282.4	2	UniProt (Q9NXA8) Pfam (PF02146)	Homo sapiens (human)	Regulatory protein SIR2 homolog 5,SIR2-like protein 5
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
3	D, F (A, B)	3-[3-[[2-[(2-chlorophenyl)amino]-5-[[(1~{S})-1-phenylpropyl]carbamoyl]pyrimidin-4-yl]amino]propylcarbamothioylamino]propanoic acid	non-polymer		570.1	2	Chemie (A1EZP)
4	G, H (A, B)	water	water		18.0	82	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58564.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1271.0
All*	Total formula weight	59835.8

*Water molecules are not included.