9WZO

Crystal structure of 5-HT2AR in complex with antipsychotic drug pimavanserin

This is a non-PDB format compatible entry.

Summary for 9WZO

• Entry DOI: 10.2210/pdb9wzo/pdb
• Descriptor: 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562, CHOLESTEROL, PENTAETHYLENE GLYCOL, ... (7 entities in total)
• Functional Keywords: gpcr, dopamine receptor, serotonin receptor, pimavanserin, antipsychotic, 5ht2ar, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 47724.26

Authors

Tang, L.,Cao, D.,Wang, S. (deposition date: 2025-09-29, release date: 2026-10-07)

• Primary citation: He, L.,Tang, L.,Cao, D.,Duan, W.,Yu, J.,Zhang, P.,Li, H.,Wang, Y.,Meng, B.,Wang, H.,Zhou, Y.,Li, B.,Liu, X.,Liu, Z.,Zhang, L.,Cheng, J.,Wang, S.; Mechanisms Underlying Sustained Antidepressant Effects of Psychedelics Inspire Microdosing Strategies; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)