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9WS3

Crystal structure of phosphorylated PAK2 kinase domain containing K278R mutant

Summary for 9WS3
Entry DOI10.2210/pdb9ws3/pdb
DescriptorPAK-2p34, GUANIDINE, CHLORIDE ION, ... (4 entities in total)
Functional Keywordskinase fold, active conformation, phosphorylation at thr402, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight34991.26
Authors
Chen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X. (deposition date: 2025-09-12, release date: 2026-09-16)
Primary citationChen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X.
Kinetic and structural insights into the autoactivation of PAK2 kinase domain: A research paradigm for studying self-activating enzyme
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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