9WS3
Crystal structure of phosphorylated PAK2 kinase domain containing K278R mutant
Summary for 9WS3
| Entry DOI | 10.2210/pdb9ws3/pdb |
| Descriptor | PAK-2p34, GUANIDINE, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | kinase fold, active conformation, phosphorylation at thr402, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34991.26 |
| Authors | Chen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X. (deposition date: 2025-09-12, release date: 2026-09-16) |
| Primary citation | Chen, F.Y.,Hu, H.-F.,Wang, J.,Luo, Z.P.,Wu, J.-W.,Wang, Z.-X. Kinetic and structural insights into the autoactivation of PAK2 kinase domain: A research paradigm for studying self-activating enzyme To Be Published, |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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