9WS3
Crystal structure of phosphorylated PAK2 kinase domain containing K278R mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PAK-2p34 | polymer | 309 | 34861.3 | 1 | UniProt (Q13177) Pfam (PF00069) | Homo sapiens (human) | Serine/threonine-protein kinase PAK 2,p34,C-t-PAK2 |
| 2 | B (A) | GUANIDINE | non-polymer | 59.1 | 1 | Chemie (GAI) PubChem (3520) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 4 | E (A) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 227 - 524 (UniProt: Q13177)
| PDB | External Database | Details |
|---|---|---|
| Met 224 | - | initiating methionine |
| Ala 225 | - | expression tag |
| Ser 226 | - | expression tag |
| Arg 278 | Lys 278 | engineered mutation |
| Leu 525 | - | expression tag |
| Glu 526 | - | expression tag |
| His 527 | - | expression tag |
| His 528 | - | expression tag |
| His 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34861.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 130.0 | |
| All* | Total formula weight | 34991.3 |
