9WQA

5-HT2B receptor bound to IHCH-1906 in complex with an antibody obtained by cryo-electron microscopy (cryoEM)

This is a non-PDB format compatible entry.

Summary for 9WQA

• Entry DOI: 10.2210/pdb9wqa/pdb
• EMDB information: 66164
• Descriptor: 5-hydroxytryptamine receptor 2B, Anti-5-HT2B Fab light chain, Anti-5-HT2B Fab heavy chain, ... (4 entities in total)
• Functional Keywords: gpcr, serotonin receptor, membrane protein, 5-ht2ar, signaling protein/immune system, signaling protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 85763.15

Authors

Li, H.,Tang, L.,Zhang, J.,Meng, B.,Cao, D.,Yu, J.,Liu, Z.,Wang, S.,Cheng, J. (deposition date: 2025-09-10, release date: 2026-09-16)

• Primary citation: Li, H.,Tang, J.,Zhang, J.,Meng, B.,Cao, D.,Yu, J.,Liu, Z.,Wang, S.,Cheng, J.; Structure-based design of subtype-selective psychedelic analogues; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.28 Å)