9WNE

Cryo-EM structure of the LbCas12a-Lid2-crRNA-DNA complex

Summary for 9WNE

• Entry DOI: 10.2210/pdb9wne/pdb
• EMDB information: 66115
• Descriptor: Cpf1, crRNA, DNA (39-MER), ... (6 entities in total)
• Functional Keywords: crispr-cas, rna binding protein-dna complex, rna binding protein
• Biological source: Lachnospiraceae bacterium ND2006; More
• Total number of polymer chains: 4
• Total formula weight: 182451.86

Authors

Omura, S.N.,Warren Villegas, R.,Van der Oost, J.,Nureki, O. (deposition date: 2025-09-04, release date: 2026-10-14)

• Primary citation: Warren Villegas, R.,Omura, S.N.,Castro, D.R.,Sudfeld, C.,Luteijn, M.,Morinaga, H.,Inoue, W.J.,Shuto, Y.,Vleesschauwer, D.D.,Staals, R.H.J.,Nureki, O.,Wu, W.Y.,Van der Oost, J.; Engineering and characterization of a novel Cas12a nickase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.54 Å)