9WKX

[M322I] Menin complexed with DS-1594

Summary for 9WKX

• Entry DOI: 10.2210/pdb9wkx/pdb
• Descriptor: Menin, (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: human menin, transcription, m322i mutant inhibitor complex, ds1594
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 110893.92

Authors

Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M. (deposition date: 2025-09-01, release date: 2026-04-29)

• Primary citation: Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M.; Wild-type Menin complexed with DS-1594; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)