9WKU

Wild-type Menin complexed with JNJ-75276617

Summary for 9WKU

• Entry DOI: 10.2210/pdb9wku/pdb
• Descriptor: Menin, N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: human menin, transcription, m322i mutant inhibitor complex, sndx-5613
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 111012.85

Authors

Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M. (deposition date: 2025-09-01, release date: 2026-04-29, Last modification date: 2026-05-13)

• Primary citation: Bijpuria, S.,Mckeever, B.M.,Mcgeehan, G.M.; Wild-type Menin complexed with JNJ-75276617; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)