9WIJ

Cryo-EM structure of GPR84 with GLPG1205

This is a non-PDB format compatible entry.

Summary for 9WIJ

• Entry DOI: 10.2210/pdb9wij/pdb
• EMDB information: 65995
• Descriptor: G-protein coupled receptor 84,Soluble cytochrome b562, 9-(2-cyclopropylethynyl)-2-[[(2~{S})-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one (2 entities in total)
• Functional Keywords: gpcr, signaling protein, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 50615.99

Authors

Suzuki, S.,Nishikawa, K.,Tran, D.P.,Akio, K.,Fujiyoshi, Y. (deposition date: 2025-08-28, release date: 2026-07-01)

• Primary citation: Suzuki, S.,Nishikawa, K.,Tran, D.P.,Akio, K.,Fujiyoshi, Y.; Mechanistic insight into signal bias by the agonist-dependent conformational dynamics of GPR84; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.05 Å)