9WDB

Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 S239C microtubule

Summary for 9WDB

Entry DOI	10.2210/pdb9wdb/pdb
EMDB information	65888
Descriptor	Tubulin alpha-1A chain, Tubulin beta-3 chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	cytoskeleton, microtubules, human tubulin isotypes, paclitaxel, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	102632.93
Authors	Ti, S.C.,Luo, J.Y.,Khoo, C.J. (deposition date: 2025-08-18, release date: 2026-04-01)
Primary citation	Luo, J.Y.,Khoo, C.J.,Chen, W.X.,Liu, Z.,Li, B.X.,Lau, W.S.,Li, X.D.,Ti, S.J. Allosteric modulation of paclitaxel efficacy by human tubulin variants To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.39 Å)

Structure validation