9WDB
Paclitaxel/GMPCPP-stabilized human alpha1A/beta3 S239C microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (a) | Tubulin alpha-1A chain | polymer | 451 | 50188.4 | 1 | UniProt (Q71U36) | Homo sapiens (human) | Alpha-tubulin 3,Tubulin B-alpha-1,Tubulin alpha-3 chain |
| 2 | B (b) | Tubulin beta-3 chain | polymer | 450 | 50497.6 | 1 | UniProt (Q13509) | Homo sapiens (human) | Tubulin beta-4 chain,Tubulin beta-III |
| 3 | C (a) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | D, F (a, b) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | E (b) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (16757828) PubChem (16760674) PubChem (4666) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (16760177) PubChem (16742549) PubChem (24848897) PubChem (24867246) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (24754091) PubChem (24207713) PubChem (24791027) PubChem (25200067) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (46781469) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (49868078) PubChem (45489039) PubChem (46782671) PubChem (54259298) PubChem (71209844) PubChem (57908851) PubChem (57946364) PubChem (58803237) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (59844545) PubChem (54259299) PubChem (59904698) PubChem (60123443) PubChem (57489669) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (70943371) PubChem (71096818) PubChem (5460441) PubChem (14060298) PubChem (176586897) PubChem (177678861) PubChem (73759783) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (9854162) PubChem (73707502) PubChem (73759704) PubChem (9897470) PubChem (10033513) PubChem (10485732) PubChem (11506104) PubChem (89493063) PubChem (11828953) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (15983941) PubChem (91885464) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (121459571) PubChem (122361554) PubChem (101598423) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (118528174) PubChem (11320430) PubChem (11354895) PubChem (134368714) PubChem (134972678) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (137705323) PubChem (138106885) PubChem (126761000) PubChem (140731501) PubChem (140512017) PubChem (133052515) PubChem (133640187) PubChem (146034004) PubChem (153289350) PubChem (154037993) PubChem (134715514) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (143890766) PubChem (168322423) PubChem (152743329) PubChem (169917882) PubChem (171036874) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (175758871) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) | |||
| 6 | G (b) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (G2P) |
Sequence modifications
b: 1 - 450 (UniProt: Q13509)
| PDB | External Database | Details |
|---|---|---|
| Cys 239 | Ser 239 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100686.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1946.9 | |
| All* | Total formula weight | 102632.9 |
