9WAK

Cryo-EM structure of a human sodium pump W931R mutant in ouabain-bound E2P state

Summary for 9WAK

Entry DOI	10.2210/pdb9wak/pdb
EMDB information	65821
Descriptor	Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, SODIUM ION, ... (7 entities in total)
Functional Keywords	p-type atpase, na+, k+, atpase, na/k-atpase, cation pump, transporter, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	149221.30
Authors	Abe, K.,Gopalasingam, C.C. (deposition date: 2025-08-12, release date: 2026-05-27)
Primary citation	Artigas, P.,Abe, K. Passive aberrant currents are induced by all Na pump variants causing hypomagnesemia To Be Published,
Experimental method	ELECTRON MICROSCOPY (2.86 Å)

Structure validation