9W6W

5-CT-bound serotonin 5A (5-HT5A) receptor-Gi protein complex

Summary for 9W6W

• Entry DOI: 10.2210/pdb9w6w/pdb
• EMDB information: 65707
• Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... (6 entities in total)
• Functional Keywords: serotonin receptor 5a, gi-coupled, 5-carboxamidotryptamine, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 169726.80

Authors

Zhang, X.,Xie, L.,Chen, P.,Yu, J.,Tian, X.,Wei, J.,Shao, Z.,Yan, W.,Xu, Z. (deposition date: 2025-08-05, release date: 2025-11-26)

• Primary citation: Zhang, X.,Xie, L.,Chen, P.,Yu, J.,Tian, X.,Wang, L.,Wei, J.,Shao, Z.,Yan, W.,Xu, Z.; Structural and Functional Basis for Biased Agonism at the 5-hydroxytryptamine 5A Receptor.; Mol Biomed, 6:107-107, 2025; PubMed: 41222804; DOI: 10.1186/s43556-025-00359-3

Experimental method

ELECTRON MICROSCOPY (3.13 Å)