9W2N

Crystal structure of the mutant LC3B in complex with p62

Summary for 9W2N

• Entry DOI: 10.2210/pdb9w2n/pdb
• Descriptor: Microtubule-associated protein 1 light chain 3 beta, Sequestosome-1, SULFATE ION, ... (7 entities in total)
• Functional Keywords: p62-lir bound, autophagy, engineered lc3b, atg8-ortholog, lipid binding protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 17031.67

Authors

Mathur, S.,Pal, R.K.,Biswal, B.K.,Thukral, L. (deposition date: 2025-07-28, release date: 2026-07-29)

• Primary citation: Gahlot, D.,Castin, J.,Mathur, S.,Das, D.,Kumar, A.,Arun, A.,Gain, C.,Sharma, M.,Pal, R.K.,Jain, N.,Biswal, B.K.,Singh, R.,Thukral, L.; A novel lipid-triggered allosteric site modulates LC3-LIR receptor binding activity; Biorxiv, 2026; DOI: 10.64898/2026.03.10.710726

Experimental method

X-RAY DIFFRACTION (1.67 Å)