9W2N
Crystal structure of the mutant LC3B in complex with p62
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Microtubule-associated protein 1 light chain 3 beta | polymer | 131 | 15546.8 | 1 | UniProt (Q9CQV6) Pfam (PF02991) | Mus musculus (house mouse) | Autophagy-related protein LC3 B,Autophagy-related ubiquitin-like modifier LC3 B,MAP1 light chain 3-like protein 2,Microtubule-associated proteins 1A/1B light chain 3B,MAP1A/MAP1B LC3 B,MAP1A/MAP1B light chain 3 B |
| 2 | B (C) | Sequestosome-1 | polymer | 11 | 1190.2 | 1 | UniProt (Q64337) | Mus musculus | STONE14,Ubiquitin-binding protein p62 |
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | F, G (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | H, I (A, C) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 1 - 125 (UniProt: Q9CQV6)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Lys 64 | Ile 64 | engineered mutation |
| Asp 89 | Val 89 | engineered mutation |
| Phe 91 | Val 91 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16736.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 294.8 | |
| All* | Total formula weight | 17031.7 |
