9VZG

Harnessing Noncovalent Dimerization Enables an Orally Active STING Agonist for Respiratory Syncytial Virus Therapy

This is a non-PDB format compatible entry.

Summary for 9VZG

• Entry DOI: 10.2210/pdb9vzg/pdb
• Descriptor: Stimulator of interferon genes protein, (1~{R},2~{S})-2-[(3-fluoranyl-5,6-dimethoxy-1-benzoselenophen-2-yl)carbonyl]cyclobutane-1-carboxylic acid (3 entities in total)
• Functional Keywords: sting agonist, rsv, complex, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22155.69

Authors

Bian, J.L.,Pan, L.X.,Li, Z.Y.,Guo, M.,Liu, D.Y.,Yang, L.Y. (deposition date: 2025-07-22, release date: 2026-07-29)

• Primary citation: Bian, J.L.,Pan, L.X.,Li, Z.Y.,Guo, M.,Liu, D.Y.,Yang, L.Y.; Harnessing Noncovalent Dimerization Enables an Orally Active STING Agonist for Respiratory Syncytial Virus Therapy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)