9VZG
Harnessing Noncovalent Dimerization Enables an Orally Active STING Agonist for Respiratory Syncytial Virus Therapy
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 190 | 21770.4 | 1 | UniProt (Q86WV6) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | (1~{R},2~{S})-2-[(3-fluoranyl-5,6-dimethoxy-1-benzoselenophen-2-yl)carbonyl]cyclobutane-1-carboxylic acid | non-polymer | 385.2 | 1 | Chemie (A1EUO) | |||
| 3 | C (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21770.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 385.2 | |
| All* | Total formula weight | 22155.7 |
