9VO8

Co-crystal structure of HPK1 in complex with compound 15

This is a non-PDB format compatible entry.

Summary for 9VO8

• Entry DOI: 10.2210/pdb9vo8/pdb
• Descriptor: Mitogen-activated protein kinase kinase kinase kinase 1, ~{N}-[6-[[5-chloranyl-2-[[3-[(dimethylamino)methyl]-1-methyl-indol-5-yl]amino]pyrimidin-4-yl]amino]quinoxalin-5-yl]methanesulfonamide (3 entities in total)
• Functional Keywords: hpk1, map4k1, inhibitor, complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 66834.59

Authors

Yun, C.H.,Yan, X.E.,Zhang, Y.D. (deposition date: 2025-07-01, release date: 2026-07-08)

• Primary citation: Yun, C.H.,Yan, X.E.,Zhang, Y.D.; Co-crystal structure of HPK1 in complex with compound 15; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.46 Å)