9VO8
Co-crystal structure of HPK1 in complex with compound 15
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase kinase 1 | polymer | 293 | 32865.2 | 2 | UniProt (Q92918) Pfam (PF00069) | Homo sapiens (human) | Hematopoietic progenitor kinase,MAPK/ERK kinase kinase kinase 1,MEK kinase kinase 1,MEKKK 1 |
| 2 | C, D (A, B) | ~{N}-[6-[[5-chloranyl-2-[[3-[(dimethylamino)methyl]-1-methyl-indol-5-yl]amino]pyrimidin-4-yl]amino]quinoxalin-5-yl]methanesulfonamide | non-polymer | 552.1 | 2 | Chemie (A1EUJ) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65730.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1104.1 | |
| All* | Total formula weight | 66834.6 |
