9VI9

Cryo-EM Structure of NPFFR1 in complex with peptide RFRP-3

Summary for 9VI9

Entry DOI	10.2210/pdb9vi9/pdb
EMDB information	65081
Descriptor	Neuropeptide FF receptor 1, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	gpcr, npffr1, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	145756.28
Authors	Na, M.,Xu, F. (deposition date: 2025-06-17, release date: 2025-12-03)
Primary citation	Na, M.,Yue, Y.,Xu, K.,Xu, Z.,Zhang, L.,Zhou, F.,De Neve, J.,Ballet, S.,Xu, F. Molecular Recognition at the Opioid-modulating Neuropeptide FF Receptor 1. Protein Cell, 2025 Cited by PubMed: 41206054 DOI: 10.1093/procel/pwaf090 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.02 Å)

Structure validation