9VFL

Crystal structure of PLCG1 SH2(C) domain with a triple Tyr phosphorylated peptide derived from NTRK1

Summary for 9VFL

Entry DOI	10.2210/pdb9vfl/pdb
Descriptor	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, High affinity nerve growth factor receptor, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	kinase, sh2 domain, tyr phosphorylation, signaling protein, oncoprotein
Biological source	Homo sapiens (human) More
Total number of polymer chains	24
Total formula weight	163449.39
Authors	Weng, Y.,Zheng, Q.,Pan, M.,Chen, P.,Tian, R. (deposition date: 2025-06-11, release date: 2026-06-17)
Primary citation	Weng, Y.,Zheng, Q.,Pan, M.,Chen, P.,Tian, R. Crystal structure of PLCG1 SH2(C) domain with triple phosphorylated peptide derived from NTRK1 To Be Published,
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation