9VFL
Crystal structure of PLCG1 SH2(C) domain with a triple Tyr phosphorylated peptide derived from NTRK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | polymer | 96 | 11367.1 | 12 | UniProt (P19174) Pfam (PF00017) | Homo sapiens (human) | PLC-148,Phosphoinositide phospholipase C-gamma-1,Phospholipase C-II,PLC-II,Phospholipase C-gamma-1,PLC-gamma-1 |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | High affinity nerve growth factor receptor | polymer | 16 | 2152.0 | 12 | UniProt (P04629) | Homo sapiens | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
| 3 | AA, BA, EA, HA, IA... (C, D, E, G, L...) | CHLORIDE ION | non-polymer | 35.5 | 13 | Chemie (CL) PubChem (312) | |||
| 4 | CA, DA, FA, GA, KA... (E, G, I, M, Q...) | PHOSPHATE ION | non-polymer | 95.0 | 8 | Chemie (PO4) PubChem (1061) | |||
| 5 | AB, BB, CB, DB, EB... (H, I, J, K, L...) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, S, U, W: 7 - 97 (UniProt: P19174)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Pro 4 | - | expression tag |
| Glu 5 | - | expression tag |
| Phe 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 162228.7 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1220.7 | |
| All* | Total formula weight | 163449.4 |
