9V9T

Cryo-EM structure of the ncPRC1.6 complex bound to the H2AK119ubH2BK120ub-modified nucleosome

Summary for 9V9T

• Entry DOI: 10.2210/pdb9v9t/pdb
• EMDB information: 64887
• Descriptor: RING1 and YY1-binding protein, Histone H3, Histone H4, ... (9 entities in total)
• Functional Keywords: nucleosome modification, transcriptional regulation, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 257935.87

Authors

Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J. (deposition date: 2025-06-02, release date: 2026-06-10)

• Primary citation: Yu, Y.,Cai, D.,Zhang, Y.Z.,Huang, J.; Structural mechanisms of PRC1-mediated interplay between gene repression and activation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)