9V6U

The cryo-EM structure of FD4 bound Lewy fold fibril.

Summary for 9V6U

Entry DOI	10.2210/pdb9v6u/pdb
EMDB information	64808
Descriptor	Alpha-synuclein, (2~{R})-1-fluoranyl-3-[[2-[(~{E})-2-[5-[6-(methylamino)pyridin-3-yl]pyridin-2-yl]ethenyl]-1,3-benzothiazol-6-yl]oxy]propan-2-ol (2 entities in total)
Functional Keywords	amyloid, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	15
Total formula weight	224142.89
Authors	Zhao, Q.Y.,Cui, B.Y.,Liu, C.,Li, D. (deposition date: 2025-05-27, release date: 2026-06-03)
Primary citation	Zhao, Q.Y.,Cui, B.Y.,Liu, C.,Li, D. The cryo-EM structure of FD4 bound Lewy fold fibril. To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation