Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9V6U

The cryo-EM structure of FD4 bound Lewy fold fibril.

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
c0000122biological_processnegative regulation of transcription by RNA polymerase II
c0000149molecular_functionSNARE binding
c0000287molecular_functionmagnesium ion binding
c0000976molecular_functiontranscription cis-regulatory region binding
c0001774biological_processmicroglial cell activation
c0001921biological_processpositive regulation of receptor recycling
c0001963biological_processsynaptic transmission, dopaminergic
c0003779molecular_functionactin binding
c0004857molecular_functionenzyme inhibitor activity
c0004860molecular_functionprotein kinase inhibitor activity
c0004869molecular_functioncysteine-type endopeptidase inhibitor activity
c0005504molecular_functionfatty acid binding
c0005507molecular_functioncopper ion binding
c0005509molecular_functioncalcium ion binding
c0005515molecular_functionprotein binding
c0005543molecular_functionphospholipid binding
c0005576cellular_componentextracellular region
c0005634cellular_componentnucleus
c0005640cellular_componentnuclear outer membrane
c0005737cellular_componentcytoplasm
c0005739cellular_componentmitochondrion
c0005741cellular_componentmitochondrial outer membrane
c0005743cellular_componentmitochondrial inner membrane
c0005759cellular_componentmitochondrial matrix
c0005764cellular_componentlysosome
c0005829cellular_componentcytosol
c0005840cellular_componentribosome
c0005886cellular_componentplasma membrane
c0005938cellular_componentcell cortex
c0006749biological_processglutathione metabolic process
c0008017molecular_functionmicrotubule binding
c0008021cellular_componentsynaptic vesicle
c0008047molecular_functionenzyme activator activity
c0008198molecular_functionferrous iron binding
c0008270molecular_functionzinc ion binding
c0008289molecular_functionlipid binding
c0010040biological_processresponse to iron(II) ion
c0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
c0014059biological_processregulation of dopamine secretion
c0015629cellular_componentactin cytoskeleton
c0015631molecular_functiontubulin binding
c0016020cellular_componentmembrane
c0016079biological_processsynaptic vesicle exocytosis
c0016082biological_processsynaptic vesicle priming
c0016234cellular_componentinclusion body
c0016491molecular_functionoxidoreductase activity
c0019894molecular_functionkinesin binding
c0019899molecular_functionenzyme binding
c0019904molecular_functionprotein domain specific binding
c0030424cellular_componentaxon
c0030426cellular_componentgrowth cone
c0030544molecular_functionHsp70 protein binding
c0030659cellular_componentcytoplasmic vesicle membrane
c0030672cellular_componentsynaptic vesicle membrane
c0031092cellular_componentplatelet alpha granule membrane
c0031115biological_processnegative regulation of microtubule polymerization
c0031623biological_processreceptor internalization
c0031648biological_processprotein destabilization
c0032026biological_processresponse to magnesium ion
c0032496biological_processresponse to lipopolysaccharide
c0032991cellular_componentprotein-containing complex
c0034341biological_processresponse to type II interferon
c0034599biological_processcellular response to oxidative stress
c0035493biological_processSNARE complex assembly
c0035543biological_processpositive regulation of SNARE complex assembly
c0042220biological_processresponse to cocaine
c0042393molecular_functionhistone binding
c0042416biological_processdopamine biosynthetic process
c0042802molecular_functionidentical protein binding
c0043014molecular_functionalpha-tubulin binding
c0043025cellular_componentneuronal cell body
c0043065biological_processpositive regulation of apoptotic process
c0043066biological_processnegative regulation of apoptotic process
c0043195cellular_componentterminal bouton
c0043274molecular_functionphospholipase binding
c0043524biological_processnegative regulation of neuron apoptotic process
c0043679cellular_componentaxon terminus
c0044344biological_processcellular response to fibroblast growth factor stimulus
c0045202cellular_componentsynapse
c0045807biological_processpositive regulation of endocytosis
c0045920biological_processnegative regulation of exocytosis
c0045921biological_processpositive regulation of exocytosis
c0045963biological_processnegative regulation of dopamine metabolic process
c0048148biological_processbehavioral response to cocaine
c0048156molecular_functiontau protein binding
c0048471cellular_componentperinuclear region of cytoplasm
c0048487molecular_functionbeta-tubulin binding
c0048488biological_processsynaptic vesicle endocytosis
c0048489biological_processsynaptic vesicle transport
c0050729biological_processpositive regulation of inflammatory response
c0050808biological_processsynapse organization
c0051219molecular_functionphosphoprotein binding
c0051262biological_processprotein tetramerization
c0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
c0051583biological_processdopamine uptake involved in synaptic transmission
c0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
c0051612biological_processnegative regulation of serotonin uptake
c0051621biological_processregulation of norepinephrine uptake
c0051622biological_processnegative regulation of norepinephrine uptake
c0055074biological_processcalcium ion homeostasis
c0060732biological_processpositive regulation of inositol phosphate biosynthetic process
c0060961molecular_functionphospholipase D inhibitor activity
c0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
c0070507biological_processregulation of microtubule cytoskeleton organization
c0070555biological_processresponse to interleukin-1
c0070840molecular_functiondynein complex binding
c0071280biological_processcellular response to copper ion
c0071872biological_processcellular response to epinephrine stimulus
c0097413cellular_componentLewy body
c0097435biological_processsupramolecular fiber organization
c0098793cellular_componentpresynapse
c0099512cellular_componentsupramolecular fiber
c0140311molecular_functionprotein sequestering activity
c0141108molecular_functiontransporter regulator activity
c1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
c1903136molecular_functioncuprous ion binding
c1903285biological_processpositive regulation of hydrogen peroxide catabolic process
c1903421biological_processregulation of synaptic vesicle recycling
c1903426biological_processregulation of reactive oxygen species biosynthetic process
c1904307biological_processresponse to desipramine
c1904377biological_processpositive regulation of protein localization to cell periphery
c1904715biological_processnegative regulation of chaperone-mediated autophagy
c1905606biological_processregulation of presynapse assembly
c1990000biological_processamyloid fibril formation
d0000122biological_processnegative regulation of transcription by RNA polymerase II
d0000149molecular_functionSNARE binding
d0000287molecular_functionmagnesium ion binding
d0000976molecular_functiontranscription cis-regulatory region binding
d0001774biological_processmicroglial cell activation
d0001921biological_processpositive regulation of receptor recycling
d0001963biological_processsynaptic transmission, dopaminergic
d0003779molecular_functionactin binding
d0004857molecular_functionenzyme inhibitor activity
d0004860molecular_functionprotein kinase inhibitor activity
d0004869molecular_functioncysteine-type endopeptidase inhibitor activity
d0005504molecular_functionfatty acid binding
d0005507molecular_functioncopper ion binding
d0005509molecular_functioncalcium ion binding
d0005515molecular_functionprotein binding
d0005543molecular_functionphospholipid binding
d0005576cellular_componentextracellular region
d0005634cellular_componentnucleus
d0005640cellular_componentnuclear outer membrane
d0005737cellular_componentcytoplasm
d0005739cellular_componentmitochondrion
d0005741cellular_componentmitochondrial outer membrane
d0005743cellular_componentmitochondrial inner membrane
d0005759cellular_componentmitochondrial matrix
d0005764cellular_componentlysosome
d0005829cellular_componentcytosol
d0005840cellular_componentribosome
d0005886cellular_componentplasma membrane
d0005938cellular_componentcell cortex
d0006749biological_processglutathione metabolic process
d0008017molecular_functionmicrotubule binding
d0008021cellular_componentsynaptic vesicle
d0008047molecular_functionenzyme activator activity
d0008198molecular_functionferrous iron binding
d0008270molecular_functionzinc ion binding
d0008289molecular_functionlipid binding
d0010040biological_processresponse to iron(II) ion
d0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
d0014059biological_processregulation of dopamine secretion
d0015629cellular_componentactin cytoskeleton
d0015631molecular_functiontubulin binding
d0016020cellular_componentmembrane
d0016079biological_processsynaptic vesicle exocytosis
d0016082biological_processsynaptic vesicle priming
d0016234cellular_componentinclusion body
d0016491molecular_functionoxidoreductase activity
d0019894molecular_functionkinesin binding
d0019899molecular_functionenzyme binding
d0019904molecular_functionprotein domain specific binding
d0030424cellular_componentaxon
d0030426cellular_componentgrowth cone
d0030544molecular_functionHsp70 protein binding
d0030659cellular_componentcytoplasmic vesicle membrane
d0030672cellular_componentsynaptic vesicle membrane
d0031092cellular_componentplatelet alpha granule membrane
d0031115biological_processnegative regulation of microtubule polymerization
d0031623biological_processreceptor internalization
d0031648biological_processprotein destabilization
d0032026biological_processresponse to magnesium ion
d0032496biological_processresponse to lipopolysaccharide
d0032991cellular_componentprotein-containing complex
d0034341biological_processresponse to type II interferon
d0034599biological_processcellular response to oxidative stress
d0035493biological_processSNARE complex assembly
d0035543biological_processpositive regulation of SNARE complex assembly
d0042220biological_processresponse to cocaine
d0042393molecular_functionhistone binding
d0042416biological_processdopamine biosynthetic process
d0042802molecular_functionidentical protein binding
d0043014molecular_functionalpha-tubulin binding
d0043025cellular_componentneuronal cell body
d0043065biological_processpositive regulation of apoptotic process
d0043066biological_processnegative regulation of apoptotic process
d0043195cellular_componentterminal bouton
d0043274molecular_functionphospholipase binding
d0043524biological_processnegative regulation of neuron apoptotic process
d0043679cellular_componentaxon terminus
d0044344biological_processcellular response to fibroblast growth factor stimulus
d0045202cellular_componentsynapse
d0045807biological_processpositive regulation of endocytosis
d0045920biological_processnegative regulation of exocytosis
d0045921biological_processpositive regulation of exocytosis
d0045963biological_processnegative regulation of dopamine metabolic process
d0048148biological_processbehavioral response to cocaine
d0048156molecular_functiontau protein binding
d0048471cellular_componentperinuclear region of cytoplasm
d0048487molecular_functionbeta-tubulin binding
d0048488biological_processsynaptic vesicle endocytosis
d0048489biological_processsynaptic vesicle transport
d0050729biological_processpositive regulation of inflammatory response
d0050808biological_processsynapse organization
d0051219molecular_functionphosphoprotein binding
d0051262biological_processprotein tetramerization
d0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
d0051583biological_processdopamine uptake involved in synaptic transmission
d0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
d0051612biological_processnegative regulation of serotonin uptake
d0051621biological_processregulation of norepinephrine uptake
d0051622biological_processnegative regulation of norepinephrine uptake
d0055074biological_processcalcium ion homeostasis
d0060732biological_processpositive regulation of inositol phosphate biosynthetic process
d0060961molecular_functionphospholipase D inhibitor activity
d0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
d0070507biological_processregulation of microtubule cytoskeleton organization
d0070555biological_processresponse to interleukin-1
d0070840molecular_functiondynein complex binding
d0071280biological_processcellular response to copper ion
d0071872biological_processcellular response to epinephrine stimulus
d0097413cellular_componentLewy body
d0097435biological_processsupramolecular fiber organization
d0098793cellular_componentpresynapse
d0099512cellular_componentsupramolecular fiber
d0140311molecular_functionprotein sequestering activity
d0141108molecular_functiontransporter regulator activity
d1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
d1903136molecular_functioncuprous ion binding
d1903285biological_processpositive regulation of hydrogen peroxide catabolic process
d1903421biological_processregulation of synaptic vesicle recycling
d1903426biological_processregulation of reactive oxygen species biosynthetic process
d1904307biological_processresponse to desipramine
d1904377biological_processpositive regulation of protein localization to cell periphery
d1904715biological_processnegative regulation of chaperone-mediated autophagy
d1905606biological_processregulation of presynapse assembly
d1990000biological_processamyloid fibril formation
e0000122biological_processnegative regulation of transcription by RNA polymerase II
e0000149molecular_functionSNARE binding
e0000287molecular_functionmagnesium ion binding
e0000976molecular_functiontranscription cis-regulatory region binding
e0001774biological_processmicroglial cell activation
e0001921biological_processpositive regulation of receptor recycling
e0001963biological_processsynaptic transmission, dopaminergic
e0003779molecular_functionactin binding
e0004857molecular_functionenzyme inhibitor activity
e0004860molecular_functionprotein kinase inhibitor activity
e0004869molecular_functioncysteine-type endopeptidase inhibitor activity
e0005504molecular_functionfatty acid binding
e0005507molecular_functioncopper ion binding
e0005509molecular_functioncalcium ion binding
e0005515molecular_functionprotein binding
e0005543molecular_functionphospholipid binding
e0005576cellular_componentextracellular region
e0005634cellular_componentnucleus
e0005640cellular_componentnuclear outer membrane
e0005737cellular_componentcytoplasm
e0005739cellular_componentmitochondrion
e0005741cellular_componentmitochondrial outer membrane
e0005743cellular_componentmitochondrial inner membrane
e0005759cellular_componentmitochondrial matrix
e0005764cellular_componentlysosome
e0005829cellular_componentcytosol
e0005840cellular_componentribosome
e0005886cellular_componentplasma membrane
e0005938cellular_componentcell cortex
e0006749biological_processglutathione metabolic process
e0008017molecular_functionmicrotubule binding
e0008021cellular_componentsynaptic vesicle
e0008047molecular_functionenzyme activator activity
e0008198molecular_functionferrous iron binding
e0008270molecular_functionzinc ion binding
e0008289molecular_functionlipid binding
e0010040biological_processresponse to iron(II) ion
e0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
e0014059biological_processregulation of dopamine secretion
e0015629cellular_componentactin cytoskeleton
e0015631molecular_functiontubulin binding
e0016020cellular_componentmembrane
e0016079biological_processsynaptic vesicle exocytosis
e0016082biological_processsynaptic vesicle priming
e0016234cellular_componentinclusion body
e0016491molecular_functionoxidoreductase activity
e0019894molecular_functionkinesin binding
e0019899molecular_functionenzyme binding
e0019904molecular_functionprotein domain specific binding
e0030424cellular_componentaxon
e0030426cellular_componentgrowth cone
e0030544molecular_functionHsp70 protein binding
e0030659cellular_componentcytoplasmic vesicle membrane
e0030672cellular_componentsynaptic vesicle membrane
e0031092cellular_componentplatelet alpha granule membrane
e0031115biological_processnegative regulation of microtubule polymerization
e0031623biological_processreceptor internalization
e0031648biological_processprotein destabilization
e0032026biological_processresponse to magnesium ion
e0032496biological_processresponse to lipopolysaccharide
e0032991cellular_componentprotein-containing complex
e0034341biological_processresponse to type II interferon
e0034599biological_processcellular response to oxidative stress
e0035493biological_processSNARE complex assembly
e0035543biological_processpositive regulation of SNARE complex assembly
e0042220biological_processresponse to cocaine
e0042393molecular_functionhistone binding
e0042416biological_processdopamine biosynthetic process
e0042802molecular_functionidentical protein binding
e0043014molecular_functionalpha-tubulin binding
e0043025cellular_componentneuronal cell body
e0043065biological_processpositive regulation of apoptotic process
e0043066biological_processnegative regulation of apoptotic process
e0043195cellular_componentterminal bouton
e0043274molecular_functionphospholipase binding
e0043524biological_processnegative regulation of neuron apoptotic process
e0043679cellular_componentaxon terminus
e0044344biological_processcellular response to fibroblast growth factor stimulus
e0045202cellular_componentsynapse
e0045807biological_processpositive regulation of endocytosis
e0045920biological_processnegative regulation of exocytosis
e0045921biological_processpositive regulation of exocytosis
e0045963biological_processnegative regulation of dopamine metabolic process
e0048148biological_processbehavioral response to cocaine
e0048156molecular_functiontau protein binding
e0048471cellular_componentperinuclear region of cytoplasm
e0048487molecular_functionbeta-tubulin binding
e0048488biological_processsynaptic vesicle endocytosis
e0048489biological_processsynaptic vesicle transport
e0050729biological_processpositive regulation of inflammatory response
e0050808biological_processsynapse organization
e0051219molecular_functionphosphoprotein binding
e0051262biological_processprotein tetramerization
e0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
e0051583biological_processdopamine uptake involved in synaptic transmission
e0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
e0051612biological_processnegative regulation of serotonin uptake
e0051621biological_processregulation of norepinephrine uptake
e0051622biological_processnegative regulation of norepinephrine uptake
e0055074biological_processcalcium ion homeostasis
e0060732biological_processpositive regulation of inositol phosphate biosynthetic process
e0060961molecular_functionphospholipase D inhibitor activity
e0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
e0070507biological_processregulation of microtubule cytoskeleton organization
e0070555biological_processresponse to interleukin-1
e0070840molecular_functiondynein complex binding
e0071280biological_processcellular response to copper ion
e0071872biological_processcellular response to epinephrine stimulus
e0097413cellular_componentLewy body
e0097435biological_processsupramolecular fiber organization
e0098793cellular_componentpresynapse
e0099512cellular_componentsupramolecular fiber
e0140311molecular_functionprotein sequestering activity
e0141108molecular_functiontransporter regulator activity
e1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
e1903136molecular_functioncuprous ion binding
e1903285biological_processpositive regulation of hydrogen peroxide catabolic process
e1903421biological_processregulation of synaptic vesicle recycling
e1903426biological_processregulation of reactive oxygen species biosynthetic process
e1904307biological_processresponse to desipramine
e1904377biological_processpositive regulation of protein localization to cell periphery
e1904715biological_processnegative regulation of chaperone-mediated autophagy
e1905606biological_processregulation of presynapse assembly
e1990000biological_processamyloid fibril formation
f0000122biological_processnegative regulation of transcription by RNA polymerase II
f0000149molecular_functionSNARE binding
f0000287molecular_functionmagnesium ion binding
f0000976molecular_functiontranscription cis-regulatory region binding
f0001774biological_processmicroglial cell activation
f0001921biological_processpositive regulation of receptor recycling
f0001963biological_processsynaptic transmission, dopaminergic
f0003779molecular_functionactin binding
f0004857molecular_functionenzyme inhibitor activity
f0004860molecular_functionprotein kinase inhibitor activity
f0004869molecular_functioncysteine-type endopeptidase inhibitor activity
f0005504molecular_functionfatty acid binding
f0005507molecular_functioncopper ion binding
f0005509molecular_functioncalcium ion binding
f0005515molecular_functionprotein binding
f0005543molecular_functionphospholipid binding
f0005576cellular_componentextracellular region
f0005634cellular_componentnucleus
f0005640cellular_componentnuclear outer membrane
f0005737cellular_componentcytoplasm
f0005739cellular_componentmitochondrion
f0005741cellular_componentmitochondrial outer membrane
f0005743cellular_componentmitochondrial inner membrane
f0005759cellular_componentmitochondrial matrix
f0005764cellular_componentlysosome
f0005829cellular_componentcytosol
f0005840cellular_componentribosome
f0005886cellular_componentplasma membrane
f0005938cellular_componentcell cortex
f0006749biological_processglutathione metabolic process
f0008017molecular_functionmicrotubule binding
f0008021cellular_componentsynaptic vesicle
f0008047molecular_functionenzyme activator activity
f0008198molecular_functionferrous iron binding
f0008270molecular_functionzinc ion binding
f0008289molecular_functionlipid binding
f0010040biological_processresponse to iron(II) ion
f0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
f0014059biological_processregulation of dopamine secretion
f0015629cellular_componentactin cytoskeleton
f0015631molecular_functiontubulin binding
f0016020cellular_componentmembrane
f0016079biological_processsynaptic vesicle exocytosis
f0016082biological_processsynaptic vesicle priming
f0016234cellular_componentinclusion body
f0016491molecular_functionoxidoreductase activity
f0019894molecular_functionkinesin binding
f0019899molecular_functionenzyme binding
f0019904molecular_functionprotein domain specific binding
f0030424cellular_componentaxon
f0030426cellular_componentgrowth cone
f0030544molecular_functionHsp70 protein binding
f0030659cellular_componentcytoplasmic vesicle membrane
f0030672cellular_componentsynaptic vesicle membrane
f0031092cellular_componentplatelet alpha granule membrane
f0031115biological_processnegative regulation of microtubule polymerization
f0031623biological_processreceptor internalization
f0031648biological_processprotein destabilization
f0032026biological_processresponse to magnesium ion
f0032496biological_processresponse to lipopolysaccharide
f0032991cellular_componentprotein-containing complex
f0034341biological_processresponse to type II interferon
f0034599biological_processcellular response to oxidative stress
f0035493biological_processSNARE complex assembly
f0035543biological_processpositive regulation of SNARE complex assembly
f0042220biological_processresponse to cocaine
f0042393molecular_functionhistone binding
f0042416biological_processdopamine biosynthetic process
f0042802molecular_functionidentical protein binding
f0043014molecular_functionalpha-tubulin binding
f0043025cellular_componentneuronal cell body
f0043065biological_processpositive regulation of apoptotic process
f0043066biological_processnegative regulation of apoptotic process
f0043195cellular_componentterminal bouton
f0043274molecular_functionphospholipase binding
f0043524biological_processnegative regulation of neuron apoptotic process
f0043679cellular_componentaxon terminus
f0044344biological_processcellular response to fibroblast growth factor stimulus
f0045202cellular_componentsynapse
f0045807biological_processpositive regulation of endocytosis
f0045920biological_processnegative regulation of exocytosis
f0045921biological_processpositive regulation of exocytosis
f0045963biological_processnegative regulation of dopamine metabolic process
f0048148biological_processbehavioral response to cocaine
f0048156molecular_functiontau protein binding
f0048471cellular_componentperinuclear region of cytoplasm
f0048487molecular_functionbeta-tubulin binding
f0048488biological_processsynaptic vesicle endocytosis
f0048489biological_processsynaptic vesicle transport
f0050729biological_processpositive regulation of inflammatory response
f0050808biological_processsynapse organization
f0051219molecular_functionphosphoprotein binding
f0051262biological_processprotein tetramerization
f0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
f0051583biological_processdopamine uptake involved in synaptic transmission
f0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
f0051612biological_processnegative regulation of serotonin uptake
f0051621biological_processregulation of norepinephrine uptake
f0051622biological_processnegative regulation of norepinephrine uptake
f0055074biological_processcalcium ion homeostasis
f0060732biological_processpositive regulation of inositol phosphate biosynthetic process
f0060961molecular_functionphospholipase D inhibitor activity
f0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
f0070507biological_processregulation of microtubule cytoskeleton organization
f0070555biological_processresponse to interleukin-1
f0070840molecular_functiondynein complex binding
f0071280biological_processcellular response to copper ion
f0071872biological_processcellular response to epinephrine stimulus
f0097413cellular_componentLewy body
f0097435biological_processsupramolecular fiber organization
f0098793cellular_componentpresynapse
f0099512cellular_componentsupramolecular fiber
f0140311molecular_functionprotein sequestering activity
f0141108molecular_functiontransporter regulator activity
f1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
f1903136molecular_functioncuprous ion binding
f1903285biological_processpositive regulation of hydrogen peroxide catabolic process
f1903421biological_processregulation of synaptic vesicle recycling
f1903426biological_processregulation of reactive oxygen species biosynthetic process
f1904307biological_processresponse to desipramine
f1904377biological_processpositive regulation of protein localization to cell periphery
f1904715biological_processnegative regulation of chaperone-mediated autophagy
f1905606biological_processregulation of presynapse assembly
f1990000biological_processamyloid fibril formation
g0000122biological_processnegative regulation of transcription by RNA polymerase II
g0000149molecular_functionSNARE binding
g0000287molecular_functionmagnesium ion binding
g0000976molecular_functiontranscription cis-regulatory region binding
g0001774biological_processmicroglial cell activation
g0001921biological_processpositive regulation of receptor recycling
g0001963biological_processsynaptic transmission, dopaminergic
g0003779molecular_functionactin binding
g0004857molecular_functionenzyme inhibitor activity
g0004860molecular_functionprotein kinase inhibitor activity
g0004869molecular_functioncysteine-type endopeptidase inhibitor activity
g0005504molecular_functionfatty acid binding
g0005507molecular_functioncopper ion binding
g0005509molecular_functioncalcium ion binding
g0005515molecular_functionprotein binding
g0005543molecular_functionphospholipid binding
g0005576cellular_componentextracellular region
g0005634cellular_componentnucleus
g0005640cellular_componentnuclear outer membrane
g0005737cellular_componentcytoplasm
g0005739cellular_componentmitochondrion
g0005741cellular_componentmitochondrial outer membrane
g0005743cellular_componentmitochondrial inner membrane
g0005759cellular_componentmitochondrial matrix
g0005764cellular_componentlysosome
g0005829cellular_componentcytosol
g0005840cellular_componentribosome
g0005886cellular_componentplasma membrane
g0005938cellular_componentcell cortex
g0006749biological_processglutathione metabolic process
g0008017molecular_functionmicrotubule binding
g0008021cellular_componentsynaptic vesicle
g0008047molecular_functionenzyme activator activity
g0008198molecular_functionferrous iron binding
g0008270molecular_functionzinc ion binding
g0008289molecular_functionlipid binding
g0010040biological_processresponse to iron(II) ion
g0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
g0014059biological_processregulation of dopamine secretion
g0015629cellular_componentactin cytoskeleton
g0015631molecular_functiontubulin binding
g0016020cellular_componentmembrane
g0016079biological_processsynaptic vesicle exocytosis
g0016082biological_processsynaptic vesicle priming
g0016234cellular_componentinclusion body
g0016491molecular_functionoxidoreductase activity
g0019894molecular_functionkinesin binding
g0019899molecular_functionenzyme binding
g0019904molecular_functionprotein domain specific binding
g0030424cellular_componentaxon
g0030426cellular_componentgrowth cone
g0030544molecular_functionHsp70 protein binding
g0030659cellular_componentcytoplasmic vesicle membrane
g0030672cellular_componentsynaptic vesicle membrane
g0031092cellular_componentplatelet alpha granule membrane
g0031115biological_processnegative regulation of microtubule polymerization
g0031623biological_processreceptor internalization
g0031648biological_processprotein destabilization
g0032026biological_processresponse to magnesium ion
g0032496biological_processresponse to lipopolysaccharide
g0032991cellular_componentprotein-containing complex
g0034341biological_processresponse to type II interferon
g0034599biological_processcellular response to oxidative stress
g0035493biological_processSNARE complex assembly
g0035543biological_processpositive regulation of SNARE complex assembly
g0042220biological_processresponse to cocaine
g0042393molecular_functionhistone binding
g0042416biological_processdopamine biosynthetic process
g0042802molecular_functionidentical protein binding
g0043014molecular_functionalpha-tubulin binding
g0043025cellular_componentneuronal cell body
g0043065biological_processpositive regulation of apoptotic process
g0043066biological_processnegative regulation of apoptotic process
g0043195cellular_componentterminal bouton
g0043274molecular_functionphospholipase binding
g0043524biological_processnegative regulation of neuron apoptotic process
g0043679cellular_componentaxon terminus
g0044344biological_processcellular response to fibroblast growth factor stimulus
g0045202cellular_componentsynapse
g0045807biological_processpositive regulation of endocytosis
g0045920biological_processnegative regulation of exocytosis
g0045921biological_processpositive regulation of exocytosis
g0045963biological_processnegative regulation of dopamine metabolic process
g0048148biological_processbehavioral response to cocaine
g0048156molecular_functiontau protein binding
g0048471cellular_componentperinuclear region of cytoplasm
g0048487molecular_functionbeta-tubulin binding
g0048488biological_processsynaptic vesicle endocytosis
g0048489biological_processsynaptic vesicle transport
g0050729biological_processpositive regulation of inflammatory response
g0050808biological_processsynapse organization
g0051219molecular_functionphosphoprotein binding
g0051262biological_processprotein tetramerization
g0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
g0051583biological_processdopamine uptake involved in synaptic transmission
g0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
g0051612biological_processnegative regulation of serotonin uptake
g0051621biological_processregulation of norepinephrine uptake
g0051622biological_processnegative regulation of norepinephrine uptake
g0055074biological_processcalcium ion homeostasis
g0060732biological_processpositive regulation of inositol phosphate biosynthetic process
g0060961molecular_functionphospholipase D inhibitor activity
g0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
g0070507biological_processregulation of microtubule cytoskeleton organization
g0070555biological_processresponse to interleukin-1
g0070840molecular_functiondynein complex binding
g0071280biological_processcellular response to copper ion
g0071872biological_processcellular response to epinephrine stimulus
g0097413cellular_componentLewy body
g0097435biological_processsupramolecular fiber organization
g0098793cellular_componentpresynapse
g0099512cellular_componentsupramolecular fiber
g0140311molecular_functionprotein sequestering activity
g0141108molecular_functiontransporter regulator activity
g1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
g1903136molecular_functioncuprous ion binding
g1903285biological_processpositive regulation of hydrogen peroxide catabolic process
g1903421biological_processregulation of synaptic vesicle recycling
g1903426biological_processregulation of reactive oxygen species biosynthetic process
g1904307biological_processresponse to desipramine
g1904377biological_processpositive regulation of protein localization to cell periphery
g1904715biological_processnegative regulation of chaperone-mediated autophagy
g1905606biological_processregulation of presynapse assembly
g1990000biological_processamyloid fibril formation
h0000122biological_processnegative regulation of transcription by RNA polymerase II
h0000149molecular_functionSNARE binding
h0000287molecular_functionmagnesium ion binding
h0000976molecular_functiontranscription cis-regulatory region binding
h0001774biological_processmicroglial cell activation
h0001921biological_processpositive regulation of receptor recycling
h0001963biological_processsynaptic transmission, dopaminergic
h0003779molecular_functionactin binding
h0004857molecular_functionenzyme inhibitor activity
h0004860molecular_functionprotein kinase inhibitor activity
h0004869molecular_functioncysteine-type endopeptidase inhibitor activity
h0005504molecular_functionfatty acid binding
h0005507molecular_functioncopper ion binding
h0005509molecular_functioncalcium ion binding
h0005515molecular_functionprotein binding
h0005543molecular_functionphospholipid binding
h0005576cellular_componentextracellular region
h0005634cellular_componentnucleus
h0005640cellular_componentnuclear outer membrane
h0005737cellular_componentcytoplasm
h0005739cellular_componentmitochondrion
h0005741cellular_componentmitochondrial outer membrane
h0005743cellular_componentmitochondrial inner membrane
h0005759cellular_componentmitochondrial matrix
h0005764cellular_componentlysosome
h0005829cellular_componentcytosol
h0005840cellular_componentribosome
h0005886cellular_componentplasma membrane
h0005938cellular_componentcell cortex
h0006749biological_processglutathione metabolic process
h0008017molecular_functionmicrotubule binding
h0008021cellular_componentsynaptic vesicle
h0008047molecular_functionenzyme activator activity
h0008198molecular_functionferrous iron binding
h0008270molecular_functionzinc ion binding
h0008289molecular_functionlipid binding
h0010040biological_processresponse to iron(II) ion
h0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
h0014059biological_processregulation of dopamine secretion
h0015629cellular_componentactin cytoskeleton
h0015631molecular_functiontubulin binding
h0016020cellular_componentmembrane
h0016079biological_processsynaptic vesicle exocytosis
h0016082biological_processsynaptic vesicle priming
h0016234cellular_componentinclusion body
h0016491molecular_functionoxidoreductase activity
h0019894molecular_functionkinesin binding
h0019899molecular_functionenzyme binding
h0019904molecular_functionprotein domain specific binding
h0030424cellular_componentaxon
h0030426cellular_componentgrowth cone
h0030544molecular_functionHsp70 protein binding
h0030659cellular_componentcytoplasmic vesicle membrane
h0030672cellular_componentsynaptic vesicle membrane
h0031092cellular_componentplatelet alpha granule membrane
h0031115biological_processnegative regulation of microtubule polymerization
h0031623biological_processreceptor internalization
h0031648biological_processprotein destabilization
h0032026biological_processresponse to magnesium ion
h0032496biological_processresponse to lipopolysaccharide
h0032991cellular_componentprotein-containing complex
h0034341biological_processresponse to type II interferon
h0034599biological_processcellular response to oxidative stress
h0035493biological_processSNARE complex assembly
h0035543biological_processpositive regulation of SNARE complex assembly
h0042220biological_processresponse to cocaine
h0042393molecular_functionhistone binding
h0042416biological_processdopamine biosynthetic process
h0042802molecular_functionidentical protein binding
h0043014molecular_functionalpha-tubulin binding
h0043025cellular_componentneuronal cell body
h0043065biological_processpositive regulation of apoptotic process
h0043066biological_processnegative regulation of apoptotic process
h0043195cellular_componentterminal bouton
h0043274molecular_functionphospholipase binding
h0043524biological_processnegative regulation of neuron apoptotic process
h0043679cellular_componentaxon terminus
h0044344biological_processcellular response to fibroblast growth factor stimulus
h0045202cellular_componentsynapse
h0045807biological_processpositive regulation of endocytosis
h0045920biological_processnegative regulation of exocytosis
h0045921biological_processpositive regulation of exocytosis
h0045963biological_processnegative regulation of dopamine metabolic process
h0048148biological_processbehavioral response to cocaine
h0048156molecular_functiontau protein binding
h0048471cellular_componentperinuclear region of cytoplasm
h0048487molecular_functionbeta-tubulin binding
h0048488biological_processsynaptic vesicle endocytosis
h0048489biological_processsynaptic vesicle transport
h0050729biological_processpositive regulation of inflammatory response
h0050808biological_processsynapse organization
h0051219molecular_functionphosphoprotein binding
h0051262biological_processprotein tetramerization
h0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
h0051583biological_processdopamine uptake involved in synaptic transmission
h0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
h0051612biological_processnegative regulation of serotonin uptake
h0051621biological_processregulation of norepinephrine uptake
h0051622biological_processnegative regulation of norepinephrine uptake
h0055074biological_processcalcium ion homeostasis
h0060732biological_processpositive regulation of inositol phosphate biosynthetic process
h0060961molecular_functionphospholipase D inhibitor activity
h0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
h0070507biological_processregulation of microtubule cytoskeleton organization
h0070555biological_processresponse to interleukin-1
h0070840molecular_functiondynein complex binding
h0071280biological_processcellular response to copper ion
h0071872biological_processcellular response to epinephrine stimulus
h0097413cellular_componentLewy body
h0097435biological_processsupramolecular fiber organization
h0098793cellular_componentpresynapse
h0099512cellular_componentsupramolecular fiber
h0140311molecular_functionprotein sequestering activity
h0141108molecular_functiontransporter regulator activity
h1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
h1903136molecular_functioncuprous ion binding
h1903285biological_processpositive regulation of hydrogen peroxide catabolic process
h1903421biological_processregulation of synaptic vesicle recycling
h1903426biological_processregulation of reactive oxygen species biosynthetic process
h1904307biological_processresponse to desipramine
h1904377biological_processpositive regulation of protein localization to cell periphery
h1904715biological_processnegative regulation of chaperone-mediated autophagy
h1905606biological_processregulation of presynapse assembly
h1990000biological_processamyloid fibril formation
i0000122biological_processnegative regulation of transcription by RNA polymerase II
i0000149molecular_functionSNARE binding
i0000287molecular_functionmagnesium ion binding
i0000976molecular_functiontranscription cis-regulatory region binding
i0001774biological_processmicroglial cell activation
i0001921biological_processpositive regulation of receptor recycling
i0001963biological_processsynaptic transmission, dopaminergic
i0003779molecular_functionactin binding
i0004857molecular_functionenzyme inhibitor activity
i0004860molecular_functionprotein kinase inhibitor activity
i0004869molecular_functioncysteine-type endopeptidase inhibitor activity
i0005504molecular_functionfatty acid binding
i0005507molecular_functioncopper ion binding
i0005509molecular_functioncalcium ion binding
i0005515molecular_functionprotein binding
i0005543molecular_functionphospholipid binding
i0005576cellular_componentextracellular region
i0005634cellular_componentnucleus
i0005640cellular_componentnuclear outer membrane
i0005737cellular_componentcytoplasm
i0005739cellular_componentmitochondrion
i0005741cellular_componentmitochondrial outer membrane
i0005743cellular_componentmitochondrial inner membrane
i0005759cellular_componentmitochondrial matrix
i0005764cellular_componentlysosome
i0005829cellular_componentcytosol
i0005840cellular_componentribosome
i0005886cellular_componentplasma membrane
i0005938cellular_componentcell cortex
i0006749biological_processglutathione metabolic process
i0008017molecular_functionmicrotubule binding
i0008021cellular_componentsynaptic vesicle
i0008047molecular_functionenzyme activator activity
i0008198molecular_functionferrous iron binding
i0008270molecular_functionzinc ion binding
i0008289molecular_functionlipid binding
i0010040biological_processresponse to iron(II) ion
i0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
i0014059biological_processregulation of dopamine secretion
i0015629cellular_componentactin cytoskeleton
i0015631molecular_functiontubulin binding
i0016020cellular_componentmembrane
i0016079biological_processsynaptic vesicle exocytosis
i0016082biological_processsynaptic vesicle priming
i0016234cellular_componentinclusion body
i0016491molecular_functionoxidoreductase activity
i0019894molecular_functionkinesin binding
i0019899molecular_functionenzyme binding
i0019904molecular_functionprotein domain specific binding
i0030424cellular_componentaxon
i0030426cellular_componentgrowth cone
i0030544molecular_functionHsp70 protein binding
i0030659cellular_componentcytoplasmic vesicle membrane
i0030672cellular_componentsynaptic vesicle membrane
i0031092cellular_componentplatelet alpha granule membrane
i0031115biological_processnegative regulation of microtubule polymerization
i0031623biological_processreceptor internalization
i0031648biological_processprotein destabilization
i0032026biological_processresponse to magnesium ion
i0032496biological_processresponse to lipopolysaccharide
i0032991cellular_componentprotein-containing complex
i0034341biological_processresponse to type II interferon
i0034599biological_processcellular response to oxidative stress
i0035493biological_processSNARE complex assembly
i0035543biological_processpositive regulation of SNARE complex assembly
i0042220biological_processresponse to cocaine
i0042393molecular_functionhistone binding
i0042416biological_processdopamine biosynthetic process
i0042802molecular_functionidentical protein binding
i0043014molecular_functionalpha-tubulin binding
i0043025cellular_componentneuronal cell body
i0043065biological_processpositive regulation of apoptotic process
i0043066biological_processnegative regulation of apoptotic process
i0043195cellular_componentterminal bouton
i0043274molecular_functionphospholipase binding
i0043524biological_processnegative regulation of neuron apoptotic process
i0043679cellular_componentaxon terminus
i0044344biological_processcellular response to fibroblast growth factor stimulus
i0045202cellular_componentsynapse
i0045807biological_processpositive regulation of endocytosis
i0045920biological_processnegative regulation of exocytosis
i0045921biological_processpositive regulation of exocytosis
i0045963biological_processnegative regulation of dopamine metabolic process
i0048148biological_processbehavioral response to cocaine
i0048156molecular_functiontau protein binding
i0048471cellular_componentperinuclear region of cytoplasm
i0048487molecular_functionbeta-tubulin binding
i0048488biological_processsynaptic vesicle endocytosis
i0048489biological_processsynaptic vesicle transport
i0050729biological_processpositive regulation of inflammatory response
i0050808biological_processsynapse organization
i0051219molecular_functionphosphoprotein binding
i0051262biological_processprotein tetramerization
i0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
i0051583biological_processdopamine uptake involved in synaptic transmission
i0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
i0051612biological_processnegative regulation of serotonin uptake
i0051621biological_processregulation of norepinephrine uptake
i0051622biological_processnegative regulation of norepinephrine uptake
i0055074biological_processcalcium ion homeostasis
i0060732biological_processpositive regulation of inositol phosphate biosynthetic process
i0060961molecular_functionphospholipase D inhibitor activity
i0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
i0070507biological_processregulation of microtubule cytoskeleton organization
i0070555biological_processresponse to interleukin-1
i0070840molecular_functiondynein complex binding
i0071280biological_processcellular response to copper ion
i0071872biological_processcellular response to epinephrine stimulus
i0097413cellular_componentLewy body
i0097435biological_processsupramolecular fiber organization
i0098793cellular_componentpresynapse
i0099512cellular_componentsupramolecular fiber
i0140311molecular_functionprotein sequestering activity
i0141108molecular_functiontransporter regulator activity
i1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
i1903136molecular_functioncuprous ion binding
i1903285biological_processpositive regulation of hydrogen peroxide catabolic process
i1903421biological_processregulation of synaptic vesicle recycling
i1903426biological_processregulation of reactive oxygen species biosynthetic process
i1904307biological_processresponse to desipramine
i1904377biological_processpositive regulation of protein localization to cell periphery
i1904715biological_processnegative regulation of chaperone-mediated autophagy
i1905606biological_processregulation of presynapse assembly
i1990000biological_processamyloid fibril formation
j0000122biological_processnegative regulation of transcription by RNA polymerase II
j0000149molecular_functionSNARE binding
j0000287molecular_functionmagnesium ion binding
j0000976molecular_functiontranscription cis-regulatory region binding
j0001774biological_processmicroglial cell activation
j0001921biological_processpositive regulation of receptor recycling
j0001963biological_processsynaptic transmission, dopaminergic
j0003779molecular_functionactin binding
j0004857molecular_functionenzyme inhibitor activity
j0004860molecular_functionprotein kinase inhibitor activity
j0004869molecular_functioncysteine-type endopeptidase inhibitor activity
j0005504molecular_functionfatty acid binding
j0005507molecular_functioncopper ion binding
j0005509molecular_functioncalcium ion binding
j0005515molecular_functionprotein binding
j0005543molecular_functionphospholipid binding
j0005576cellular_componentextracellular region
j0005634cellular_componentnucleus
j0005640cellular_componentnuclear outer membrane
j0005737cellular_componentcytoplasm
j0005739cellular_componentmitochondrion
j0005741cellular_componentmitochondrial outer membrane
j0005743cellular_componentmitochondrial inner membrane
j0005759cellular_componentmitochondrial matrix
j0005764cellular_componentlysosome
j0005829cellular_componentcytosol
j0005840cellular_componentribosome
j0005886cellular_componentplasma membrane
j0005938cellular_componentcell cortex
j0006749biological_processglutathione metabolic process
j0008017molecular_functionmicrotubule binding
j0008021cellular_componentsynaptic vesicle
j0008047molecular_functionenzyme activator activity
j0008198molecular_functionferrous iron binding
j0008270molecular_functionzinc ion binding
j0008289molecular_functionlipid binding
j0010040biological_processresponse to iron(II) ion
j0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
j0014059biological_processregulation of dopamine secretion
j0015629cellular_componentactin cytoskeleton
j0015631molecular_functiontubulin binding
j0016020cellular_componentmembrane
j0016079biological_processsynaptic vesicle exocytosis
j0016082biological_processsynaptic vesicle priming
j0016234cellular_componentinclusion body
j0016491molecular_functionoxidoreductase activity
j0019894molecular_functionkinesin binding
j0019899molecular_functionenzyme binding
j0019904molecular_functionprotein domain specific binding
j0030424cellular_componentaxon
j0030426cellular_componentgrowth cone
j0030544molecular_functionHsp70 protein binding
j0030659cellular_componentcytoplasmic vesicle membrane
j0030672cellular_componentsynaptic vesicle membrane
j0031092cellular_componentplatelet alpha granule membrane
j0031115biological_processnegative regulation of microtubule polymerization
j0031623biological_processreceptor internalization
j0031648biological_processprotein destabilization
j0032026biological_processresponse to magnesium ion
j0032496biological_processresponse to lipopolysaccharide
j0032991cellular_componentprotein-containing complex
j0034341biological_processresponse to type II interferon
j0034599biological_processcellular response to oxidative stress
j0035493biological_processSNARE complex assembly
j0035543biological_processpositive regulation of SNARE complex assembly
j0042220biological_processresponse to cocaine
j0042393molecular_functionhistone binding
j0042416biological_processdopamine biosynthetic process
j0042802molecular_functionidentical protein binding
j0043014molecular_functionalpha-tubulin binding
j0043025cellular_componentneuronal cell body
j0043065biological_processpositive regulation of apoptotic process
j0043066biological_processnegative regulation of apoptotic process
j0043195cellular_componentterminal bouton
j0043274molecular_functionphospholipase binding
j0043524biological_processnegative regulation of neuron apoptotic process
j0043679cellular_componentaxon terminus
j0044344biological_processcellular response to fibroblast growth factor stimulus
j0045202cellular_componentsynapse
j0045807biological_processpositive regulation of endocytosis
j0045920biological_processnegative regulation of exocytosis
j0045921biological_processpositive regulation of exocytosis
j0045963biological_processnegative regulation of dopamine metabolic process
j0048148biological_processbehavioral response to cocaine
j0048156molecular_functiontau protein binding
j0048471cellular_componentperinuclear region of cytoplasm
j0048487molecular_functionbeta-tubulin binding
j0048488biological_processsynaptic vesicle endocytosis
j0048489biological_processsynaptic vesicle transport
j0050729biological_processpositive regulation of inflammatory response
j0050808biological_processsynapse organization
j0051219molecular_functionphosphoprotein binding
j0051262biological_processprotein tetramerization
j0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
j0051583biological_processdopamine uptake involved in synaptic transmission
j0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
j0051612biological_processnegative regulation of serotonin uptake
j0051621biological_processregulation of norepinephrine uptake
j0051622biological_processnegative regulation of norepinephrine uptake
j0055074biological_processcalcium ion homeostasis
j0060732biological_processpositive regulation of inositol phosphate biosynthetic process
j0060961molecular_functionphospholipase D inhibitor activity
j0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
j0070507biological_processregulation of microtubule cytoskeleton organization
j0070555biological_processresponse to interleukin-1
j0070840molecular_functiondynein complex binding
j0071280biological_processcellular response to copper ion
j0071872biological_processcellular response to epinephrine stimulus
j0097413cellular_componentLewy body
j0097435biological_processsupramolecular fiber organization
j0098793cellular_componentpresynapse
j0099512cellular_componentsupramolecular fiber
j0140311molecular_functionprotein sequestering activity
j0141108molecular_functiontransporter regulator activity
j1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
j1903136molecular_functioncuprous ion binding
j1903285biological_processpositive regulation of hydrogen peroxide catabolic process
j1903421biological_processregulation of synaptic vesicle recycling
j1903426biological_processregulation of reactive oxygen species biosynthetic process
j1904307biological_processresponse to desipramine
j1904377biological_processpositive regulation of protein localization to cell periphery
j1904715biological_processnegative regulation of chaperone-mediated autophagy
j1905606biological_processregulation of presynapse assembly
j1990000biological_processamyloid fibril formation
k0000122biological_processnegative regulation of transcription by RNA polymerase II
k0000149molecular_functionSNARE binding
k0000287molecular_functionmagnesium ion binding
k0000976molecular_functiontranscription cis-regulatory region binding
k0001774biological_processmicroglial cell activation
k0001921biological_processpositive regulation of receptor recycling
k0001963biological_processsynaptic transmission, dopaminergic
k0003779molecular_functionactin binding
k0004857molecular_functionenzyme inhibitor activity
k0004860molecular_functionprotein kinase inhibitor activity
k0004869molecular_functioncysteine-type endopeptidase inhibitor activity
k0005504molecular_functionfatty acid binding
k0005507molecular_functioncopper ion binding
k0005509molecular_functioncalcium ion binding
k0005515molecular_functionprotein binding
k0005543molecular_functionphospholipid binding
k0005576cellular_componentextracellular region
k0005634cellular_componentnucleus
k0005640cellular_componentnuclear outer membrane
k0005737cellular_componentcytoplasm
k0005739cellular_componentmitochondrion
k0005741cellular_componentmitochondrial outer membrane
k0005743cellular_componentmitochondrial inner membrane
k0005759cellular_componentmitochondrial matrix
k0005764cellular_componentlysosome
k0005829cellular_componentcytosol
k0005840cellular_componentribosome
k0005886cellular_componentplasma membrane
k0005938cellular_componentcell cortex
k0006749biological_processglutathione metabolic process
k0008017molecular_functionmicrotubule binding
k0008021cellular_componentsynaptic vesicle
k0008047molecular_functionenzyme activator activity
k0008198molecular_functionferrous iron binding
k0008270molecular_functionzinc ion binding
k0008289molecular_functionlipid binding
k0010040biological_processresponse to iron(II) ion
k0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
k0014059biological_processregulation of dopamine secretion
k0015629cellular_componentactin cytoskeleton
k0015631molecular_functiontubulin binding
k0016020cellular_componentmembrane
k0016079biological_processsynaptic vesicle exocytosis
k0016082biological_processsynaptic vesicle priming
k0016234cellular_componentinclusion body
k0016491molecular_functionoxidoreductase activity
k0019894molecular_functionkinesin binding
k0019899molecular_functionenzyme binding
k0019904molecular_functionprotein domain specific binding
k0030424cellular_componentaxon
k0030426cellular_componentgrowth cone
k0030544molecular_functionHsp70 protein binding
k0030659cellular_componentcytoplasmic vesicle membrane
k0030672cellular_componentsynaptic vesicle membrane
k0031092cellular_componentplatelet alpha granule membrane
k0031115biological_processnegative regulation of microtubule polymerization
k0031623biological_processreceptor internalization
k0031648biological_processprotein destabilization
k0032026biological_processresponse to magnesium ion
k0032496biological_processresponse to lipopolysaccharide
k0032991cellular_componentprotein-containing complex
k0034341biological_processresponse to type II interferon
k0034599biological_processcellular response to oxidative stress
k0035493biological_processSNARE complex assembly
k0035543biological_processpositive regulation of SNARE complex assembly
k0042220biological_processresponse to cocaine
k0042393molecular_functionhistone binding
k0042416biological_processdopamine biosynthetic process
k0042802molecular_functionidentical protein binding
k0043014molecular_functionalpha-tubulin binding
k0043025cellular_componentneuronal cell body
k0043065biological_processpositive regulation of apoptotic process
k0043066biological_processnegative regulation of apoptotic process
k0043195cellular_componentterminal bouton
k0043274molecular_functionphospholipase binding
k0043524biological_processnegative regulation of neuron apoptotic process
k0043679cellular_componentaxon terminus
k0044344biological_processcellular response to fibroblast growth factor stimulus
k0045202cellular_componentsynapse
k0045807biological_processpositive regulation of endocytosis
k0045920biological_processnegative regulation of exocytosis
k0045921biological_processpositive regulation of exocytosis
k0045963biological_processnegative regulation of dopamine metabolic process
k0048148biological_processbehavioral response to cocaine
k0048156molecular_functiontau protein binding
k0048471cellular_componentperinuclear region of cytoplasm
k0048487molecular_functionbeta-tubulin binding
k0048488biological_processsynaptic vesicle endocytosis
k0048489biological_processsynaptic vesicle transport
k0050729biological_processpositive regulation of inflammatory response
k0050808biological_processsynapse organization
k0051219molecular_functionphosphoprotein binding
k0051262biological_processprotein tetramerization
k0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
k0051583biological_processdopamine uptake involved in synaptic transmission
k0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
k0051612biological_processnegative regulation of serotonin uptake
k0051621biological_processregulation of norepinephrine uptake
k0051622biological_processnegative regulation of norepinephrine uptake
k0055074biological_processcalcium ion homeostasis
k0060732biological_processpositive regulation of inositol phosphate biosynthetic process
k0060961molecular_functionphospholipase D inhibitor activity
k0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
k0070507biological_processregulation of microtubule cytoskeleton organization
k0070555biological_processresponse to interleukin-1
k0070840molecular_functiondynein complex binding
k0071280biological_processcellular response to copper ion
k0071872biological_processcellular response to epinephrine stimulus
k0097413cellular_componentLewy body
k0097435biological_processsupramolecular fiber organization
k0098793cellular_componentpresynapse
k0099512cellular_componentsupramolecular fiber
k0140311molecular_functionprotein sequestering activity
k0141108molecular_functiontransporter regulator activity
k1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
k1903136molecular_functioncuprous ion binding
k1903285biological_processpositive regulation of hydrogen peroxide catabolic process
k1903421biological_processregulation of synaptic vesicle recycling
k1903426biological_processregulation of reactive oxygen species biosynthetic process
k1904307biological_processresponse to desipramine
k1904377biological_processpositive regulation of protein localization to cell periphery
k1904715biological_processnegative regulation of chaperone-mediated autophagy
k1905606biological_processregulation of presynapse assembly
k1990000biological_processamyloid fibril formation
o0000122biological_processnegative regulation of transcription by RNA polymerase II
o0000149molecular_functionSNARE binding
o0000287molecular_functionmagnesium ion binding
o0000976molecular_functiontranscription cis-regulatory region binding
o0001774biological_processmicroglial cell activation
o0001921biological_processpositive regulation of receptor recycling
o0001963biological_processsynaptic transmission, dopaminergic
o0003779molecular_functionactin binding
o0004857molecular_functionenzyme inhibitor activity
o0004860molecular_functionprotein kinase inhibitor activity
o0004869molecular_functioncysteine-type endopeptidase inhibitor activity
o0005504molecular_functionfatty acid binding
o0005507molecular_functioncopper ion binding
o0005509molecular_functioncalcium ion binding
o0005515molecular_functionprotein binding
o0005543molecular_functionphospholipid binding
o0005576cellular_componentextracellular region
o0005634cellular_componentnucleus
o0005640cellular_componentnuclear outer membrane
o0005737cellular_componentcytoplasm
o0005739cellular_componentmitochondrion
o0005741cellular_componentmitochondrial outer membrane
o0005743cellular_componentmitochondrial inner membrane
o0005759cellular_componentmitochondrial matrix
o0005764cellular_componentlysosome
o0005829cellular_componentcytosol
o0005840cellular_componentribosome
o0005886cellular_componentplasma membrane
o0005938cellular_componentcell cortex
o0006749biological_processglutathione metabolic process
o0008017molecular_functionmicrotubule binding
o0008021cellular_componentsynaptic vesicle
o0008047molecular_functionenzyme activator activity
o0008198molecular_functionferrous iron binding
o0008270molecular_functionzinc ion binding
o0008289molecular_functionlipid binding
o0010040biological_processresponse to iron(II) ion
o0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
o0014059biological_processregulation of dopamine secretion
o0015629cellular_componentactin cytoskeleton
o0015631molecular_functiontubulin binding
o0016020cellular_componentmembrane
o0016079biological_processsynaptic vesicle exocytosis
o0016082biological_processsynaptic vesicle priming
o0016234cellular_componentinclusion body
o0016491molecular_functionoxidoreductase activity
o0019894molecular_functionkinesin binding
o0019899molecular_functionenzyme binding
o0019904molecular_functionprotein domain specific binding
o0030424cellular_componentaxon
o0030426cellular_componentgrowth cone
o0030544molecular_functionHsp70 protein binding
o0030659cellular_componentcytoplasmic vesicle membrane
o0030672cellular_componentsynaptic vesicle membrane
o0031092cellular_componentplatelet alpha granule membrane
o0031115biological_processnegative regulation of microtubule polymerization
o0031623biological_processreceptor internalization
o0031648biological_processprotein destabilization
o0032026biological_processresponse to magnesium ion
o0032496biological_processresponse to lipopolysaccharide
o0032991cellular_componentprotein-containing complex
o0034341biological_processresponse to type II interferon
o0034599biological_processcellular response to oxidative stress
o0035493biological_processSNARE complex assembly
o0035543biological_processpositive regulation of SNARE complex assembly
o0042220biological_processresponse to cocaine
o0042393molecular_functionhistone binding
o0042416biological_processdopamine biosynthetic process
o0042802molecular_functionidentical protein binding
o0043014molecular_functionalpha-tubulin binding
o0043025cellular_componentneuronal cell body
o0043065biological_processpositive regulation of apoptotic process
o0043066biological_processnegative regulation of apoptotic process
o0043195cellular_componentterminal bouton
o0043274molecular_functionphospholipase binding
o0043524biological_processnegative regulation of neuron apoptotic process
o0043679cellular_componentaxon terminus
o0044344biological_processcellular response to fibroblast growth factor stimulus
o0045202cellular_componentsynapse
o0045807biological_processpositive regulation of endocytosis
o0045920biological_processnegative regulation of exocytosis
o0045921biological_processpositive regulation of exocytosis
o0045963biological_processnegative regulation of dopamine metabolic process
o0048148biological_processbehavioral response to cocaine
o0048156molecular_functiontau protein binding
o0048471cellular_componentperinuclear region of cytoplasm
o0048487molecular_functionbeta-tubulin binding
o0048488biological_processsynaptic vesicle endocytosis
o0048489biological_processsynaptic vesicle transport
o0050729biological_processpositive regulation of inflammatory response
o0050808biological_processsynapse organization
o0051219molecular_functionphosphoprotein binding
o0051262biological_processprotein tetramerization
o0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
o0051583biological_processdopamine uptake involved in synaptic transmission
o0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
o0051612biological_processnegative regulation of serotonin uptake
o0051621biological_processregulation of norepinephrine uptake
o0051622biological_processnegative regulation of norepinephrine uptake
o0055074biological_processcalcium ion homeostasis
o0060732biological_processpositive regulation of inositol phosphate biosynthetic process
o0060961molecular_functionphospholipase D inhibitor activity
o0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
o0070507biological_processregulation of microtubule cytoskeleton organization
o0070555biological_processresponse to interleukin-1
o0070840molecular_functiondynein complex binding
o0071280biological_processcellular response to copper ion
o0071872biological_processcellular response to epinephrine stimulus
o0097413cellular_componentLewy body
o0097435biological_processsupramolecular fiber organization
o0098793cellular_componentpresynapse
o0099512cellular_componentsupramolecular fiber
o0140311molecular_functionprotein sequestering activity
o0141108molecular_functiontransporter regulator activity
o1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
o1903136molecular_functioncuprous ion binding
o1903285biological_processpositive regulation of hydrogen peroxide catabolic process
o1903421biological_processregulation of synaptic vesicle recycling
o1903426biological_processregulation of reactive oxygen species biosynthetic process
o1904307biological_processresponse to desipramine
o1904377biological_processpositive regulation of protein localization to cell periphery
o1904715biological_processnegative regulation of chaperone-mediated autophagy
o1905606biological_processregulation of presynapse assembly
o1990000biological_processamyloid fibril formation
p0000122biological_processnegative regulation of transcription by RNA polymerase II
p0000149molecular_functionSNARE binding
p0000287molecular_functionmagnesium ion binding
p0000976molecular_functiontranscription cis-regulatory region binding
p0001774biological_processmicroglial cell activation
p0001921biological_processpositive regulation of receptor recycling
p0001963biological_processsynaptic transmission, dopaminergic
p0003779molecular_functionactin binding
p0004857molecular_functionenzyme inhibitor activity
p0004860molecular_functionprotein kinase inhibitor activity
p0004869molecular_functioncysteine-type endopeptidase inhibitor activity
p0005504molecular_functionfatty acid binding
p0005507molecular_functioncopper ion binding
p0005509molecular_functioncalcium ion binding
p0005515molecular_functionprotein binding
p0005543molecular_functionphospholipid binding
p0005576cellular_componentextracellular region
p0005634cellular_componentnucleus
p0005640cellular_componentnuclear outer membrane
p0005737cellular_componentcytoplasm
p0005739cellular_componentmitochondrion
p0005741cellular_componentmitochondrial outer membrane
p0005743cellular_componentmitochondrial inner membrane
p0005759cellular_componentmitochondrial matrix
p0005764cellular_componentlysosome
p0005829cellular_componentcytosol
p0005840cellular_componentribosome
p0005886cellular_componentplasma membrane
p0005938cellular_componentcell cortex
p0006749biological_processglutathione metabolic process
p0008017molecular_functionmicrotubule binding
p0008021cellular_componentsynaptic vesicle
p0008047molecular_functionenzyme activator activity
p0008198molecular_functionferrous iron binding
p0008270molecular_functionzinc ion binding
p0008289molecular_functionlipid binding
p0010040biological_processresponse to iron(II) ion
p0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
p0014059biological_processregulation of dopamine secretion
p0015629cellular_componentactin cytoskeleton
p0015631molecular_functiontubulin binding
p0016020cellular_componentmembrane
p0016079biological_processsynaptic vesicle exocytosis
p0016082biological_processsynaptic vesicle priming
p0016234cellular_componentinclusion body
p0016491molecular_functionoxidoreductase activity
p0019894molecular_functionkinesin binding
p0019899molecular_functionenzyme binding
p0019904molecular_functionprotein domain specific binding
p0030424cellular_componentaxon
p0030426cellular_componentgrowth cone
p0030544molecular_functionHsp70 protein binding
p0030659cellular_componentcytoplasmic vesicle membrane
p0030672cellular_componentsynaptic vesicle membrane
p0031092cellular_componentplatelet alpha granule membrane
p0031115biological_processnegative regulation of microtubule polymerization
p0031623biological_processreceptor internalization
p0031648biological_processprotein destabilization
p0032026biological_processresponse to magnesium ion
p0032496biological_processresponse to lipopolysaccharide
p0032991cellular_componentprotein-containing complex
p0034341biological_processresponse to type II interferon
p0034599biological_processcellular response to oxidative stress
p0035493biological_processSNARE complex assembly
p0035543biological_processpositive regulation of SNARE complex assembly
p0042220biological_processresponse to cocaine
p0042393molecular_functionhistone binding
p0042416biological_processdopamine biosynthetic process
p0042802molecular_functionidentical protein binding
p0043014molecular_functionalpha-tubulin binding
p0043025cellular_componentneuronal cell body
p0043065biological_processpositive regulation of apoptotic process
p0043066biological_processnegative regulation of apoptotic process
p0043195cellular_componentterminal bouton
p0043274molecular_functionphospholipase binding
p0043524biological_processnegative regulation of neuron apoptotic process
p0043679cellular_componentaxon terminus
p0044344biological_processcellular response to fibroblast growth factor stimulus
p0045202cellular_componentsynapse
p0045807biological_processpositive regulation of endocytosis
p0045920biological_processnegative regulation of exocytosis
p0045921biological_processpositive regulation of exocytosis
p0045963biological_processnegative regulation of dopamine metabolic process
p0048148biological_processbehavioral response to cocaine
p0048156molecular_functiontau protein binding
p0048471cellular_componentperinuclear region of cytoplasm
p0048487molecular_functionbeta-tubulin binding
p0048488biological_processsynaptic vesicle endocytosis
p0048489biological_processsynaptic vesicle transport
p0050729biological_processpositive regulation of inflammatory response
p0050808biological_processsynapse organization
p0051219molecular_functionphosphoprotein binding
p0051262biological_processprotein tetramerization
p0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
p0051583biological_processdopamine uptake involved in synaptic transmission
p0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
p0051612biological_processnegative regulation of serotonin uptake
p0051621biological_processregulation of norepinephrine uptake
p0051622biological_processnegative regulation of norepinephrine uptake
p0055074biological_processcalcium ion homeostasis
p0060732biological_processpositive regulation of inositol phosphate biosynthetic process
p0060961molecular_functionphospholipase D inhibitor activity
p0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
p0070507biological_processregulation of microtubule cytoskeleton organization
p0070555biological_processresponse to interleukin-1
p0070840molecular_functiondynein complex binding
p0071280biological_processcellular response to copper ion
p0071872biological_processcellular response to epinephrine stimulus
p0097413cellular_componentLewy body
p0097435biological_processsupramolecular fiber organization
p0098793cellular_componentpresynapse
p0099512cellular_componentsupramolecular fiber
p0140311molecular_functionprotein sequestering activity
p0141108molecular_functiontransporter regulator activity
p1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
p1903136molecular_functioncuprous ion binding
p1903285biological_processpositive regulation of hydrogen peroxide catabolic process
p1903421biological_processregulation of synaptic vesicle recycling
p1903426biological_processregulation of reactive oxygen species biosynthetic process
p1904307biological_processresponse to desipramine
p1904377biological_processpositive regulation of protein localization to cell periphery
p1904715biological_processnegative regulation of chaperone-mediated autophagy
p1905606biological_processregulation of presynapse assembly
p1990000biological_processamyloid fibril formation
q0000122biological_processnegative regulation of transcription by RNA polymerase II
q0000149molecular_functionSNARE binding
q0000287molecular_functionmagnesium ion binding
q0000976molecular_functiontranscription cis-regulatory region binding
q0001774biological_processmicroglial cell activation
q0001921biological_processpositive regulation of receptor recycling
q0001963biological_processsynaptic transmission, dopaminergic
q0003779molecular_functionactin binding
q0004857molecular_functionenzyme inhibitor activity
q0004860molecular_functionprotein kinase inhibitor activity
q0004869molecular_functioncysteine-type endopeptidase inhibitor activity
q0005504molecular_functionfatty acid binding
q0005507molecular_functioncopper ion binding
q0005509molecular_functioncalcium ion binding
q0005515molecular_functionprotein binding
q0005543molecular_functionphospholipid binding
q0005576cellular_componentextracellular region
q0005634cellular_componentnucleus
q0005640cellular_componentnuclear outer membrane
q0005737cellular_componentcytoplasm
q0005739cellular_componentmitochondrion
q0005741cellular_componentmitochondrial outer membrane
q0005743cellular_componentmitochondrial inner membrane
q0005759cellular_componentmitochondrial matrix
q0005764cellular_componentlysosome
q0005829cellular_componentcytosol
q0005840cellular_componentribosome
q0005886cellular_componentplasma membrane
q0005938cellular_componentcell cortex
q0006749biological_processglutathione metabolic process
q0008017molecular_functionmicrotubule binding
q0008021cellular_componentsynaptic vesicle
q0008047molecular_functionenzyme activator activity
q0008198molecular_functionferrous iron binding
q0008270molecular_functionzinc ion binding
q0008289molecular_functionlipid binding
q0010040biological_processresponse to iron(II) ion
q0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
q0014059biological_processregulation of dopamine secretion
q0015629cellular_componentactin cytoskeleton
q0015631molecular_functiontubulin binding
q0016020cellular_componentmembrane
q0016079biological_processsynaptic vesicle exocytosis
q0016082biological_processsynaptic vesicle priming
q0016234cellular_componentinclusion body
q0016491molecular_functionoxidoreductase activity
q0019894molecular_functionkinesin binding
q0019899molecular_functionenzyme binding
q0019904molecular_functionprotein domain specific binding
q0030424cellular_componentaxon
q0030426cellular_componentgrowth cone
q0030544molecular_functionHsp70 protein binding
q0030659cellular_componentcytoplasmic vesicle membrane
q0030672cellular_componentsynaptic vesicle membrane
q0031092cellular_componentplatelet alpha granule membrane
q0031115biological_processnegative regulation of microtubule polymerization
q0031623biological_processreceptor internalization
q0031648biological_processprotein destabilization
q0032026biological_processresponse to magnesium ion
q0032496biological_processresponse to lipopolysaccharide
q0032991cellular_componentprotein-containing complex
q0034341biological_processresponse to type II interferon
q0034599biological_processcellular response to oxidative stress
q0035493biological_processSNARE complex assembly
q0035543biological_processpositive regulation of SNARE complex assembly
q0042220biological_processresponse to cocaine
q0042393molecular_functionhistone binding
q0042416biological_processdopamine biosynthetic process
q0042802molecular_functionidentical protein binding
q0043014molecular_functionalpha-tubulin binding
q0043025cellular_componentneuronal cell body
q0043065biological_processpositive regulation of apoptotic process
q0043066biological_processnegative regulation of apoptotic process
q0043195cellular_componentterminal bouton
q0043274molecular_functionphospholipase binding
q0043524biological_processnegative regulation of neuron apoptotic process
q0043679cellular_componentaxon terminus
q0044344biological_processcellular response to fibroblast growth factor stimulus
q0045202cellular_componentsynapse
q0045807biological_processpositive regulation of endocytosis
q0045920biological_processnegative regulation of exocytosis
q0045921biological_processpositive regulation of exocytosis
q0045963biological_processnegative regulation of dopamine metabolic process
q0048148biological_processbehavioral response to cocaine
q0048156molecular_functiontau protein binding
q0048471cellular_componentperinuclear region of cytoplasm
q0048487molecular_functionbeta-tubulin binding
q0048488biological_processsynaptic vesicle endocytosis
q0048489biological_processsynaptic vesicle transport
q0050729biological_processpositive regulation of inflammatory response
q0050808biological_processsynapse organization
q0051219molecular_functionphosphoprotein binding
q0051262biological_processprotein tetramerization
q0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
q0051583biological_processdopamine uptake involved in synaptic transmission
q0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
q0051612biological_processnegative regulation of serotonin uptake
q0051621biological_processregulation of norepinephrine uptake
q0051622biological_processnegative regulation of norepinephrine uptake
q0055074biological_processcalcium ion homeostasis
q0060732biological_processpositive regulation of inositol phosphate biosynthetic process
q0060961molecular_functionphospholipase D inhibitor activity
q0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
q0070507biological_processregulation of microtubule cytoskeleton organization
q0070555biological_processresponse to interleukin-1
q0070840molecular_functiondynein complex binding
q0071280biological_processcellular response to copper ion
q0071872biological_processcellular response to epinephrine stimulus
q0097413cellular_componentLewy body
q0097435biological_processsupramolecular fiber organization
q0098793cellular_componentpresynapse
q0099512cellular_componentsupramolecular fiber
q0140311molecular_functionprotein sequestering activity
q0141108molecular_functiontransporter regulator activity
q1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
q1903136molecular_functioncuprous ion binding
q1903285biological_processpositive regulation of hydrogen peroxide catabolic process
q1903421biological_processregulation of synaptic vesicle recycling
q1903426biological_processregulation of reactive oxygen species biosynthetic process
q1904307biological_processresponse to desipramine
q1904377biological_processpositive regulation of protein localization to cell periphery
q1904715biological_processnegative regulation of chaperone-mediated autophagy
q1905606biological_processregulation of presynapse assembly
q1990000biological_processamyloid fibril formation
r0000122biological_processnegative regulation of transcription by RNA polymerase II
r0000149molecular_functionSNARE binding
r0000287molecular_functionmagnesium ion binding
r0000976molecular_functiontranscription cis-regulatory region binding
r0001774biological_processmicroglial cell activation
r0001921biological_processpositive regulation of receptor recycling
r0001963biological_processsynaptic transmission, dopaminergic
r0003779molecular_functionactin binding
r0004857molecular_functionenzyme inhibitor activity
r0004860molecular_functionprotein kinase inhibitor activity
r0004869molecular_functioncysteine-type endopeptidase inhibitor activity
r0005504molecular_functionfatty acid binding
r0005507molecular_functioncopper ion binding
r0005509molecular_functioncalcium ion binding
r0005515molecular_functionprotein binding
r0005543molecular_functionphospholipid binding
r0005576cellular_componentextracellular region
r0005634cellular_componentnucleus
r0005640cellular_componentnuclear outer membrane
r0005737cellular_componentcytoplasm
r0005739cellular_componentmitochondrion
r0005741cellular_componentmitochondrial outer membrane
r0005743cellular_componentmitochondrial inner membrane
r0005759cellular_componentmitochondrial matrix
r0005764cellular_componentlysosome
r0005829cellular_componentcytosol
r0005840cellular_componentribosome
r0005886cellular_componentplasma membrane
r0005938cellular_componentcell cortex
r0006749biological_processglutathione metabolic process
r0008017molecular_functionmicrotubule binding
r0008021cellular_componentsynaptic vesicle
r0008047molecular_functionenzyme activator activity
r0008198molecular_functionferrous iron binding
r0008270molecular_functionzinc ion binding
r0008289molecular_functionlipid binding
r0010040biological_processresponse to iron(II) ion
r0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
r0014059biological_processregulation of dopamine secretion
r0015629cellular_componentactin cytoskeleton
r0015631molecular_functiontubulin binding
r0016020cellular_componentmembrane
r0016079biological_processsynaptic vesicle exocytosis
r0016082biological_processsynaptic vesicle priming
r0016234cellular_componentinclusion body
r0016491molecular_functionoxidoreductase activity
r0019894molecular_functionkinesin binding
r0019899molecular_functionenzyme binding
r0019904molecular_functionprotein domain specific binding
r0030424cellular_componentaxon
r0030426cellular_componentgrowth cone
r0030544molecular_functionHsp70 protein binding
r0030659cellular_componentcytoplasmic vesicle membrane
r0030672cellular_componentsynaptic vesicle membrane
r0031092cellular_componentplatelet alpha granule membrane
r0031115biological_processnegative regulation of microtubule polymerization
r0031623biological_processreceptor internalization
r0031648biological_processprotein destabilization
r0032026biological_processresponse to magnesium ion
r0032496biological_processresponse to lipopolysaccharide
r0032991cellular_componentprotein-containing complex
r0034341biological_processresponse to type II interferon
r0034599biological_processcellular response to oxidative stress
r0035493biological_processSNARE complex assembly
r0035543biological_processpositive regulation of SNARE complex assembly
r0042220biological_processresponse to cocaine
r0042393molecular_functionhistone binding
r0042416biological_processdopamine biosynthetic process
r0042802molecular_functionidentical protein binding
r0043014molecular_functionalpha-tubulin binding
r0043025cellular_componentneuronal cell body
r0043065biological_processpositive regulation of apoptotic process
r0043066biological_processnegative regulation of apoptotic process
r0043195cellular_componentterminal bouton
r0043274molecular_functionphospholipase binding
r0043524biological_processnegative regulation of neuron apoptotic process
r0043679cellular_componentaxon terminus
r0044344biological_processcellular response to fibroblast growth factor stimulus
r0045202cellular_componentsynapse
r0045807biological_processpositive regulation of endocytosis
r0045920biological_processnegative regulation of exocytosis
r0045921biological_processpositive regulation of exocytosis
r0045963biological_processnegative regulation of dopamine metabolic process
r0048148biological_processbehavioral response to cocaine
r0048156molecular_functiontau protein binding
r0048471cellular_componentperinuclear region of cytoplasm
r0048487molecular_functionbeta-tubulin binding
r0048488biological_processsynaptic vesicle endocytosis
r0048489biological_processsynaptic vesicle transport
r0050729biological_processpositive regulation of inflammatory response
r0050808biological_processsynapse organization
r0051219molecular_functionphosphoprotein binding
r0051262biological_processprotein tetramerization
r0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
r0051583biological_processdopamine uptake involved in synaptic transmission
r0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
r0051612biological_processnegative regulation of serotonin uptake
r0051621biological_processregulation of norepinephrine uptake
r0051622biological_processnegative regulation of norepinephrine uptake
r0055074biological_processcalcium ion homeostasis
r0060732biological_processpositive regulation of inositol phosphate biosynthetic process
r0060961molecular_functionphospholipase D inhibitor activity
r0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
r0070507biological_processregulation of microtubule cytoskeleton organization
r0070555biological_processresponse to interleukin-1
r0070840molecular_functiondynein complex binding
r0071280biological_processcellular response to copper ion
r0071872biological_processcellular response to epinephrine stimulus
r0097413cellular_componentLewy body
r0097435biological_processsupramolecular fiber organization
r0098793cellular_componentpresynapse
r0099512cellular_componentsupramolecular fiber
r0140311molecular_functionprotein sequestering activity
r0141108molecular_functiontransporter regulator activity
r1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
r1903136molecular_functioncuprous ion binding
r1903285biological_processpositive regulation of hydrogen peroxide catabolic process
r1903421biological_processregulation of synaptic vesicle recycling
r1903426biological_processregulation of reactive oxygen species biosynthetic process
r1904307biological_processresponse to desipramine
r1904377biological_processpositive regulation of protein localization to cell periphery
r1904715biological_processnegative regulation of chaperone-mediated autophagy
r1905606biological_processregulation of presynapse assembly
r1990000biological_processamyloid fibril formation
s0000122biological_processnegative regulation of transcription by RNA polymerase II
s0000149molecular_functionSNARE binding
s0000287molecular_functionmagnesium ion binding
s0000976molecular_functiontranscription cis-regulatory region binding
s0001774biological_processmicroglial cell activation
s0001921biological_processpositive regulation of receptor recycling
s0001963biological_processsynaptic transmission, dopaminergic
s0003779molecular_functionactin binding
s0004857molecular_functionenzyme inhibitor activity
s0004860molecular_functionprotein kinase inhibitor activity
s0004869molecular_functioncysteine-type endopeptidase inhibitor activity
s0005504molecular_functionfatty acid binding
s0005507molecular_functioncopper ion binding
s0005509molecular_functioncalcium ion binding
s0005515molecular_functionprotein binding
s0005543molecular_functionphospholipid binding
s0005576cellular_componentextracellular region
s0005634cellular_componentnucleus
s0005640cellular_componentnuclear outer membrane
s0005737cellular_componentcytoplasm
s0005739cellular_componentmitochondrion
s0005741cellular_componentmitochondrial outer membrane
s0005743cellular_componentmitochondrial inner membrane
s0005759cellular_componentmitochondrial matrix
s0005764cellular_componentlysosome
s0005829cellular_componentcytosol
s0005840cellular_componentribosome
s0005886cellular_componentplasma membrane
s0005938cellular_componentcell cortex
s0006749biological_processglutathione metabolic process
s0008017molecular_functionmicrotubule binding
s0008021cellular_componentsynaptic vesicle
s0008047molecular_functionenzyme activator activity
s0008198molecular_functionferrous iron binding
s0008270molecular_functionzinc ion binding
s0008289molecular_functionlipid binding
s0010040biological_processresponse to iron(II) ion
s0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
s0014059biological_processregulation of dopamine secretion
s0015629cellular_componentactin cytoskeleton
s0015631molecular_functiontubulin binding
s0016020cellular_componentmembrane
s0016079biological_processsynaptic vesicle exocytosis
s0016082biological_processsynaptic vesicle priming
s0016234cellular_componentinclusion body
s0016491molecular_functionoxidoreductase activity
s0019894molecular_functionkinesin binding
s0019899molecular_functionenzyme binding
s0019904molecular_functionprotein domain specific binding
s0030424cellular_componentaxon
s0030426cellular_componentgrowth cone
s0030544molecular_functionHsp70 protein binding
s0030659cellular_componentcytoplasmic vesicle membrane
s0030672cellular_componentsynaptic vesicle membrane
s0031092cellular_componentplatelet alpha granule membrane
s0031115biological_processnegative regulation of microtubule polymerization
s0031623biological_processreceptor internalization
s0031648biological_processprotein destabilization
s0032026biological_processresponse to magnesium ion
s0032496biological_processresponse to lipopolysaccharide
s0032991cellular_componentprotein-containing complex
s0034341biological_processresponse to type II interferon
s0034599biological_processcellular response to oxidative stress
s0035493biological_processSNARE complex assembly
s0035543biological_processpositive regulation of SNARE complex assembly
s0042220biological_processresponse to cocaine
s0042393molecular_functionhistone binding
s0042416biological_processdopamine biosynthetic process
s0042802molecular_functionidentical protein binding
s0043014molecular_functionalpha-tubulin binding
s0043025cellular_componentneuronal cell body
s0043065biological_processpositive regulation of apoptotic process
s0043066biological_processnegative regulation of apoptotic process
s0043195cellular_componentterminal bouton
s0043274molecular_functionphospholipase binding
s0043524biological_processnegative regulation of neuron apoptotic process
s0043679cellular_componentaxon terminus
s0044344biological_processcellular response to fibroblast growth factor stimulus
s0045202cellular_componentsynapse
s0045807biological_processpositive regulation of endocytosis
s0045920biological_processnegative regulation of exocytosis
s0045921biological_processpositive regulation of exocytosis
s0045963biological_processnegative regulation of dopamine metabolic process
s0048148biological_processbehavioral response to cocaine
s0048156molecular_functiontau protein binding
s0048471cellular_componentperinuclear region of cytoplasm
s0048487molecular_functionbeta-tubulin binding
s0048488biological_processsynaptic vesicle endocytosis
s0048489biological_processsynaptic vesicle transport
s0050729biological_processpositive regulation of inflammatory response
s0050808biological_processsynapse organization
s0051219molecular_functionphosphoprotein binding
s0051262biological_processprotein tetramerization
s0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
s0051583biological_processdopamine uptake involved in synaptic transmission
s0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
s0051612biological_processnegative regulation of serotonin uptake
s0051621biological_processregulation of norepinephrine uptake
s0051622biological_processnegative regulation of norepinephrine uptake
s0055074biological_processcalcium ion homeostasis
s0060732biological_processpositive regulation of inositol phosphate biosynthetic process
s0060961molecular_functionphospholipase D inhibitor activity
s0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
s0070507biological_processregulation of microtubule cytoskeleton organization
s0070555biological_processresponse to interleukin-1
s0070840molecular_functiondynein complex binding
s0071280biological_processcellular response to copper ion
s0071872biological_processcellular response to epinephrine stimulus
s0097413cellular_componentLewy body
s0097435biological_processsupramolecular fiber organization
s0098793cellular_componentpresynapse
s0099512cellular_componentsupramolecular fiber
s0140311molecular_functionprotein sequestering activity
s0141108molecular_functiontransporter regulator activity
s1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
s1903136molecular_functioncuprous ion binding
s1903285biological_processpositive regulation of hydrogen peroxide catabolic process
s1903421biological_processregulation of synaptic vesicle recycling
s1903426biological_processregulation of reactive oxygen species biosynthetic process
s1904307biological_processresponse to desipramine
s1904377biological_processpositive regulation of protein localization to cell periphery
s1904715biological_processnegative regulation of chaperone-mediated autophagy
s1905606biological_processregulation of presynapse assembly
s1990000biological_processamyloid fibril formation
t0000122biological_processnegative regulation of transcription by RNA polymerase II
t0000149molecular_functionSNARE binding
t0000287molecular_functionmagnesium ion binding
t0000976molecular_functiontranscription cis-regulatory region binding
t0001774biological_processmicroglial cell activation
t0001921biological_processpositive regulation of receptor recycling
t0001963biological_processsynaptic transmission, dopaminergic
t0003779molecular_functionactin binding
t0004857molecular_functionenzyme inhibitor activity
t0004860molecular_functionprotein kinase inhibitor activity
t0004869molecular_functioncysteine-type endopeptidase inhibitor activity
t0005504molecular_functionfatty acid binding
t0005507molecular_functioncopper ion binding
t0005509molecular_functioncalcium ion binding
t0005515molecular_functionprotein binding
t0005543molecular_functionphospholipid binding
t0005576cellular_componentextracellular region
t0005634cellular_componentnucleus
t0005640cellular_componentnuclear outer membrane
t0005737cellular_componentcytoplasm
t0005739cellular_componentmitochondrion
t0005741cellular_componentmitochondrial outer membrane
t0005743cellular_componentmitochondrial inner membrane
t0005759cellular_componentmitochondrial matrix
t0005764cellular_componentlysosome
t0005829cellular_componentcytosol
t0005840cellular_componentribosome
t0005886cellular_componentplasma membrane
t0005938cellular_componentcell cortex
t0006749biological_processglutathione metabolic process
t0008017molecular_functionmicrotubule binding
t0008021cellular_componentsynaptic vesicle
t0008047molecular_functionenzyme activator activity
t0008198molecular_functionferrous iron binding
t0008270molecular_functionzinc ion binding
t0008289molecular_functionlipid binding
t0010040biological_processresponse to iron(II) ion
t0010642biological_processnegative regulation of platelet-derived growth factor receptor signaling pathway
t0014059biological_processregulation of dopamine secretion
t0015629cellular_componentactin cytoskeleton
t0015631molecular_functiontubulin binding
t0016020cellular_componentmembrane
t0016079biological_processsynaptic vesicle exocytosis
t0016082biological_processsynaptic vesicle priming
t0016234cellular_componentinclusion body
t0016491molecular_functionoxidoreductase activity
t0019894molecular_functionkinesin binding
t0019899molecular_functionenzyme binding
t0019904molecular_functionprotein domain specific binding
t0030424cellular_componentaxon
t0030426cellular_componentgrowth cone
t0030544molecular_functionHsp70 protein binding
t0030659cellular_componentcytoplasmic vesicle membrane
t0030672cellular_componentsynaptic vesicle membrane
t0031092cellular_componentplatelet alpha granule membrane
t0031115biological_processnegative regulation of microtubule polymerization
t0031623biological_processreceptor internalization
t0031648biological_processprotein destabilization
t0032026biological_processresponse to magnesium ion
t0032496biological_processresponse to lipopolysaccharide
t0032991cellular_componentprotein-containing complex
t0034341biological_processresponse to type II interferon
t0034599biological_processcellular response to oxidative stress
t0035493biological_processSNARE complex assembly
t0035543biological_processpositive regulation of SNARE complex assembly
t0042220biological_processresponse to cocaine
t0042393molecular_functionhistone binding
t0042416biological_processdopamine biosynthetic process
t0042802molecular_functionidentical protein binding
t0043014molecular_functionalpha-tubulin binding
t0043025cellular_componentneuronal cell body
t0043065biological_processpositive regulation of apoptotic process
t0043066biological_processnegative regulation of apoptotic process
t0043195cellular_componentterminal bouton
t0043274molecular_functionphospholipase binding
t0043524biological_processnegative regulation of neuron apoptotic process
t0043679cellular_componentaxon terminus
t0044344biological_processcellular response to fibroblast growth factor stimulus
t0045202cellular_componentsynapse
t0045807biological_processpositive regulation of endocytosis
t0045920biological_processnegative regulation of exocytosis
t0045921biological_processpositive regulation of exocytosis
t0045963biological_processnegative regulation of dopamine metabolic process
t0048148biological_processbehavioral response to cocaine
t0048156molecular_functiontau protein binding
t0048471cellular_componentperinuclear region of cytoplasm
t0048487molecular_functionbeta-tubulin binding
t0048488biological_processsynaptic vesicle endocytosis
t0048489biological_processsynaptic vesicle transport
t0050729biological_processpositive regulation of inflammatory response
t0050808biological_processsynapse organization
t0051219molecular_functionphosphoprotein binding
t0051262biological_processprotein tetramerization
t0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
t0051583biological_processdopamine uptake involved in synaptic transmission
t0051585biological_processnegative regulation of dopamine uptake involved in synaptic transmission
t0051612biological_processnegative regulation of serotonin uptake
t0051621biological_processregulation of norepinephrine uptake
t0051622biological_processnegative regulation of norepinephrine uptake
t0055074biological_processcalcium ion homeostasis
t0060732biological_processpositive regulation of inositol phosphate biosynthetic process
t0060961molecular_functionphospholipase D inhibitor activity
t0070495biological_processnegative regulation of thrombin-activated receptor signaling pathway
t0070507biological_processregulation of microtubule cytoskeleton organization
t0070555biological_processresponse to interleukin-1
t0070840molecular_functiondynein complex binding
t0071280biological_processcellular response to copper ion
t0071872biological_processcellular response to epinephrine stimulus
t0097413cellular_componentLewy body
t0097435biological_processsupramolecular fiber organization
t0098793cellular_componentpresynapse
t0099512cellular_componentsupramolecular fiber
t0140311molecular_functionprotein sequestering activity
t0141108molecular_functiontransporter regulator activity
t1902957biological_processnegative regulation of mitochondrial electron transport, NADH to ubiquinone
t1903136molecular_functioncuprous ion binding
t1903285biological_processpositive regulation of hydrogen peroxide catabolic process
t1903421biological_processregulation of synaptic vesicle recycling
t1903426biological_processregulation of reactive oxygen species biosynthetic process
t1904307biological_processresponse to desipramine
t1904377biological_processpositive regulation of protein localization to cell periphery
t1904715biological_processnegative regulation of chaperone-mediated autophagy
t1905606biological_processregulation of presynapse assembly
t1990000biological_processamyloid fibril formation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues210
DetailsRepeat: {"description":"3; approximate"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues150
DetailsRepeat: {"description":"4"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues15
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues15
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"10617630","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

256789

PDB entries from 2026-07-22

PDB statisticsPDBj update infoContact PDBjnumon