9V4M

Crystal structure of the T.thermophilus transcription initiation complex bound to Ap4G

This is a non-PDB format compatible entry.

Summary for 9V4M

• Entry DOI: 10.2210/pdb9v4m/pdb
• Related: 9UPW
• Descriptor: DNA-directed RNA polymerase subunit alpha, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ZINC ION, ... (12 entities in total)
• Functional Keywords: complex, transcription
• Biological source: Thermus thermophilus HB8; More
• Total number of polymer chains: 8
• Total formula weight: 445424.63

Authors

Duan, W.,Kaushik, A.,Serganov, A. (deposition date: 2025-05-24, release date: 2025-10-22)

• Primary citation: Duan, W.,Kaushik, A.,Unarta, I.C.,Wu, Y.,Liu, M.M.J.,Weaver, J.W.,Wang, B.,Rice, W.J.,Luciano, D.J.,Belasco, J.G.,Huang, X.,Nudler, E.,Serganov, A.; Molecular basis for noncanonical transcription initiation from Np4A alarmones; Nat.Chem.Biol., 2025; DOI: 10.1038/s41589-025-02044-6

Experimental method

X-RAY DIFFRACTION (3 Å)