9UVZ

Cryo-EM structure of Lysophosphatidic acid receptor 2 (LPA2)-ARK1 with Ki16425

This is a non-PDB format compatible entry.

Summary for 9UVZ

• Entry DOI: 10.2210/pdb9uvz/pdb
• EMDB information: 64542
• Descriptor: Lysophosphatidic acid receptor 2,ARK1, 3-[[4-[4-[[(1~{R})-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]methylsulfanyl]propanoic acid, SODIUM ION, ... (4 entities in total)
• Functional Keywords: gpcr, lpa2, lysophosphatidic acid receptor 2, ki16425, ark1, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 86656.35

Authors

Kojima, A.,Kawakami, K.,Kobayashi, K.,Matsui, T.E.,Uemoto, K.,Fukuda, M.,Kato, H.E. (deposition date: 2025-05-11, release date: 2026-05-06)

• Primary citation: Kojima, A.,Kawakami, K.,Kobayashi, N.,Kobayashi, K.,Matsui, T.E.,Uemoto, K.,Gu, Y.,Fukuda, M.,Kato, H.E.; A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through In Silico Construct Optimization and de novo Protein Design; Biorxiv, 2026; DOI: 10.64898/2026.04.02.716066

Experimental method

ELECTRON MICROSCOPY (2.99 Å)