9UVZ

Cryo-EM structure of Lysophosphatidic acid receptor 2 (LPA2)-ARK1 with Ki16425

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lysophosphatidic acid receptor 2,ARK1	polymer	759	86158.4	1	UniProt (Q9HBW0) Pfam (PF00001)	Homo sapiens (human)	LPA receptor 2,LPA-2,Lysophosphatidic acid receptor Edg-4
2	B (A)	3-[[4-[4-[[(1~{R})-1-(2-chlorophenyl)ethoxy]carbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]methylsulfanyl]propanoic acid	non-polymer		475.0	1	Chemie (A1L9P)
3	C (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA) PubChem (923)
4	D (A)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 1 - 219 (UniProt: Q9HBW0)

PDB	External Database	Details
Met -30	-	initiating methionine
Lys -29	-	expression tag
Thr -28	-	expression tag
Ile -27	-	expression tag
Ile -26	-	expression tag
Ala -25	-	expression tag
Leu -24	-	expression tag
Ser -23	-	expression tag
Tyr -22	-	expression tag
Ile -21	-	expression tag
Phe -20	-	expression tag
Cys -19	-	expression tag
Leu -18	-	expression tag
Val -17	-	expression tag
Phe -16	-	expression tag
Ala -15	-	expression tag
Asp -14	-	expression tag
Tyr -13	-	expression tag
Lys -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Ala -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

A: 220 - 606 (PDB: 9UVZ)
A: 607 - 722 (UniProt: Q9HBW0)

PDB	External Database	Details
Leu 723	-	expression tag
Glu 724	-	expression tag
Val 725	-	expression tag
Leu 726	-	expression tag
Phe 727	-	expression tag
Gln 728	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	86158.4
Non-Polymers*	Number of molecules	2
	Total formula weight	497.9
All*	Total formula weight	86656.4

*Water molecules are not included.