9UHX

Cryo-EM structure of the human adenosine A2A receptor bound to the antagonist ZM-241385 resolved via the fusion/crosslinking strategy

Summary for 9UHX

• Entry DOI: 10.2210/pdb9uhx/pdb
• EMDB information: 64179
• Descriptor: Adenosine receptor A2a, Green fluorescent protein, GFP-clamp, ... (4 entities in total)
• Functional Keywords: human adenosine a2a receptor; fusion/crosslinking strategy; zm-241385., membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 90523.78

Authors

Han, S.C.,Li, M.H. (deposition date: 2025-04-14, release date: 2026-10-28)

• Primary citation: Han, S.C.,Li, M.H.; Cryo-EM structure determination of GPCRs with disulfide-crosslinked fusion protein; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.03 Å)