9UED

Cryo-EM structure of human TRPV3 in complex with sevoflurane determined in MSP2N2 nanodisc

This is a non-PDB format compatible entry.

Summary for 9UED

• Entry DOI: 10.2210/pdb9ued/pdb
• EMDB information: 64082
• Descriptor: Transient receptor potential cation channel subfamily V member 3, sevoflurane, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (3 entities in total)
• Functional Keywords: transient receptor potential vanilloid 3, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 374721.42

Authors

Lu, X.,Yao, J. (deposition date: 2025-04-08, release date: 2026-04-08)

• Primary citation: Wang, P.,Zhu, J.,Lu, X.,Chen, C.,Gao, B.,Xia, K.,Pang, P.,Li, Y.,Mo, X.,Xie, C.,Li, D.,Zhang, Z.,Yao, J.; Vagal nerve TRPV3 regulates sedative-mediated appeasement; Proc.Natl.Acad.Sci.USA, 2026

Experimental method

ELECTRON MICROSCOPY (3.29 Å)