9UA3

Cryo-EM structure of neddylated CUL2-RBX1-FEM1C-ELOB-ELOC

Summary for 9UA3

Entry DOI	10.2210/pdb9ua3/pdb
EMDB information	63977
Descriptor	Protein fem-1 homolog C, Cullin-2, Elongin-B, ... (5 entities in total)
Functional Keywords	e3 ubiquitin ligase, arg/c-degron, degradation, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	360603.81
Authors	Zhou, H.,Xu, C. (deposition date: 2025-03-31, release date: 2026-03-04)
Primary citation	Zhou, H.,Israel-Gueta, M.,Chen, X.,Guo, Q.,Liu, X.,Koren, I.,Xu, C. Structural insights into CRL2FEM1C ubiquitin ligase-mediated protein ubiquitination. J Mol Cell Biol, 17:-, 2025 Cited by PubMed: 40388302 DOI: 10.1093/jmcb/mjaf016 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.28 Å)

Structure validation