9UA3
Cryo-EM structure of neddylated CUL2-RBX1-FEM1C-ELOB-ELOC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, E) | Protein fem-1 homolog C | polymer | 617 | 68767.3 | 2 | UniProt (Q96JP0) Pfam (PF12796) | Homo sapiens (human) | FEM1c,FEM1-gamma |
| 2 | B, D (B, F) | Cullin-2 | polymer | 745 | 87068.8 | 2 | UniProt (Q13617) Pfam (PF00888) Pfam (PF26557) Pfam (PF10557) | Homo sapiens (human) | CUL-2 |
| 3 | E, G (C, G) | Elongin-B | polymer | 118 | 13147.8 | 2 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 4 | F, H (D, H) | Elongin-C | polymer | 96 | 10843.4 | 2 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 5 | I, J (I, J) | ALA-ARG-ALA-ARG | polymer | 4 | 474.6 | 2 | Homo sapiens |
Sequence modifications
B, F: 2 - 745 (UniProt: Q13617)
| PDB | External Database | Details |
|---|---|---|
| Thr 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 360603.8 | |
| All* | Total formula weight | 360603.8 |
