9U4M

Focused refinement of 19S in the substrate-engaged human 26S proteasome bound to midnolin with RPT6 at top of spiral staircase

Summary for 9U4M

Entry DOI	10.2210/pdb9u4m/pdb
EMDB information	63850
Descriptor	26S proteasome non-ATPase regulatory subunit 6, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 8, ... (22 entities in total)
Functional Keywords	midnolin, 26s proteasome, complex, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	18
Total formula weight	805017.92
Authors	Zhu, C.,Qin, L.,Liang, L. (deposition date: 2025-03-19, release date: 2026-03-25)
Primary citation	Zhu, C.,Qin, L. Molecular basis for ubiquitin-independent substrate degradation by midnolin-proteasome To Be Published,
Experimental method	ELECTRON MICROSCOPY (4.14 Å)

Structure validation