9U41

GDP-bound KRAS G12D in complex with 6027

Summary for 9U41

Entry DOI	10.2210/pdb9u41/pdb
Descriptor	GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, 2-azanyl-4-[6-chloranyl-4-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoranyl-2-[[(5S,7R)-3-oxidanyl-1-adamantyl]methoxy]quinazolin-7-yl]-1-benzoselenophene-3-carbonitrile, ... (6 entities in total)
Functional Keywords	hydrolase, inhibitor, complex
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	20701.59
Authors	Zhang, Z.M.,Zhang, P. (deposition date: 2025-03-19, release date: 2026-09-23)
Primary citation	Zhang, Z.M.,Zhang, P. GDP-bound KRAS G12D in complex with 6027 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.22 Å)

Structure validation