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9U41

GDP-bound KRAS G12D in complex with 6027

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer16919449.91UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
2-azanyl-4-[6-chloranyl-4-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoranyl-2-[[(5S,7R)-3-oxidanyl-1-adamantyl]methoxy]quinazolin-7-yl]-1-benzoselenophene-3-carbonitrilenon-polymer692.11Chemie (A1EN1)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
5E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
PubChem (753)
6F
(A)
waterwater18.0258Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Asp 12Gly 12variant
Ser 118Cys 118conflict
Asp 153Glu 153conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19449.9
Non-Polymers*Number of molecules4
Total formula weight1251.7
All*Total formula weight20701.6
*Water molecules are not included.

260626

PDB entries from 2026-10-07

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