9TMM

Structure of the TCR-A targeting GPC3 [FLAELAYDL] peptide bound to HLA-A*02:01

Summary for 9TMM

• Entry DOI: 10.2210/pdb9tmm/pdb
• Descriptor: MHC class I, Beta-2-microglobulin, TCR-A alpha chain, ... (9 entities in total)
• Functional Keywords: mhc; hla; tcr; tumor; antigen; structure; hepatocarcinoma; x-ray, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 97543.30

Authors

Oyon-Olea, L.,Lopez-Sagaseta, J. (deposition date: 2025-12-15, release date: 2026-11-04)

• Primary citation: Lopez-Sagaseta, J.,Oyon-Olea, L.; Structure-function profiling identifies determinants of TCR-T cell therapeutic efficacy; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)