9TMM
Structure of the TCR-A targeting GPC3 [FLAELAYDL] peptide bound to HLA-A*02:01
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I | polymer | 280 | 32313.7 | 1 | Homo sapiens (human) | ||
| 2 | B (B) | Beta-2-microglobulin | polymer | 101 | 11936.4 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 3 | C (C) | TCR-A alpha chain | polymer | 212 | 23784.3 | 1 | Homo sapiens | ||
| 4 | D (D) | TCR-A beta chain | polymer | 244 | 27749.2 | 1 | Homo sapiens | ||
| 5 | E (P) | Glypican-3 beta subunit | polymer | 9 | 1054.2 | 1 | UniProt (P51654) | Homo sapiens (human) | |
| 6 | F, G, H, I, J... (A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 7 | O (C) | BORIC ACID | non-polymer | 61.8 | 1 | Chemie (BO3) PubChem (7628) | |||
| 8 | Q (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 9 | R, S, T, U, V (A, B, C, D, P) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
B: 2 - 100 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96837.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 705.5 | |
| All* | Total formula weight | 97543.3 |
